The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.

by Arun K Haldar, Anthony S Piro, Danielle M Pilla, Masahiro Yamamoto, Jörn Coers
Published 2014-01-01

Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells

by Arun K. Haldar, Anthony S. Piro, Ryan Finethy, Scott T. Espenschied, Hannah E. Brown, Amanda M. Giebel, Eva-Maria Frickel, David E. Nelson, Jorn Coers
Published 2016-12-01

IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins.

by Arun K Haldar, Hector A Saka, Anthony S Piro, Joe Dan Dunn, Stanley C Henry, Gregory A Taylor, Eva M Frickel, Raphael H Valdivia, Jörn Coers
Published 2013-01-01

Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins

by Ryan Finethy, Sarah Luoma, Nichole Orench-Rivera, Eric M. Feeley, Arun K. Haldar, Masahiro Yamamoto, Thirumala-Devi Kanneganti, Meta J. Kuehn, Jorn Coers, David S. Weiss, Eric J. Rubin
Published 2017-10-01