Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration

by Dmitri Kharitidi, Pirjo M. Apaja, Sanaz Manteghi, Kei Suzuki, Elena Malitskaya, Ariel Roldan, Marie-Claude Gingras, Junichi Takagi, Gergely L. Lukacs, Arnim Pause
Published 2015-10-01

Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination

by Guido Veit, Ariel Roldan, Mark A. Hancock, Dillon F. Da Fonte, Haijin Xu, Maytham Hussein, Saul Frenkiel, Elias Matouk, Tony Velkov, Gergely L. Lukacs
Published 2020-09-01

Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell

by Miklos Bagdany, Guido Veit, Ryosuke Fukuda, Radu G. Avramescu, Tsukasa Okiyoneda, Imad Baaklini, Jay Singh, Guy Sovak, Haijin Xu, Pirjo M. Apaja, Sara Sattin, Lenore K. Beitel, Ariel Roldan, Giorgio Colombo, William Balch, Jason C. Young, Gergely L. Lukacs
Published 2017-08-01