Inhibition of Bcl-xL sensitizes cells to mitotic blockers, but not mitotic drivers

by Ailsa Bennett, Olivia Sloss, Caroline Topham, Louisa Nelson, Anthony Tighe, Stephen S. Taylor
Published 2016-01-01

Distinct transcriptional programs stratify ovarian cancer cell lines into the five major histological subtypes

by Bethany M. Barnes, Louisa Nelson, Anthony Tighe, George J. Burghel, I-Hsuan Lin, Sudha Desai, Joanne C. McGrail, Robert D. Morgan, Stephen S. Taylor
Published 2021-09-01

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α

by Susana Simões-Sousa, Samantha Littler, Sarah L. Thompson, Paul Minshall, Helen Whalley, Bjorn Bakker, Klaudyna Belkot, Daniela Moralli, Daniel Bronder, Anthony Tighe, Diana C.J. Spierings, Nourdine Bah, Joshua Graham, Louisa Nelson, Catherine M. Green, Floris Foijer, Paul A. Townsend, Stephen S. Taylor
Published 2018-10-01

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

by Louisa Nelson, Anthony Tighe, Anya Golder, Samantha Littler, Bjorn Bakker, Daniela Moralli, Syed Murtuza Baker, Ian J. Donaldson, Diana C. J. Spierings, René Wardenaar, Bethanie Neale, George J. Burghel, Brett Winter-Roach, Richard Edmondson, Andrew R. Clamp, Gordon C. Jayson, Sudha Desai, Catherine M. Green, Andy Hayes, Floris Foijer, Robert D. Morgan, Stephen S. Taylor
Published 2020-02-01