Myeloid Sirtuin 2 Expression Does Not Impact Long-Term Mycobacterium tuberculosis Control.

by Filipa Cardoso, Flávia Castro, Lúcia Moreira-Teixeira, Jeremy Sousa, Egídio Torrado, Ricardo Silvestre, António Gil Castro, Margarida Saraiva, Teresa F Pais
Published 2015-01-01

High systemic IL-6 is associated with worse prognosis in patients with non-small cell lung cancer.

by Estela Maria Silva, Vânia Sammartino Mariano, Paula Roberta Aguiar Pastrez, Miguel Cordoba Pinto, António Gil Castro, Kari Juhani Syrjanen, Adhemar Longatto-Filho
Published 2017-01-01

P. brasiliensis virulence is affected by SconC, the negative regulator of inorganic sulfur assimilation.

by João Filipe Menino, Margarida Saraiva, Jéssica Gomes-Rezende, Mark Sturme, Jorge Pedrosa, António Gil Castro, Paula Ludovico, Gustavo H Goldman, Fernando Rodrigues
Published 2013-01-01

Changes in the Immune Phenotype and Gene Expression Profile Driven by a Novel Tuberculosis Nanovaccine: Short and Long-Term Post-immunization

by Amparo Martínez-Pérez, Amparo Martínez-Pérez, Ana Igea, Ana Igea, Olivia Estévez, Olivia Estévez, Catarina M. Ferreira, Catarina M. Ferreira, Egídio Torrado, Egídio Torrado, António Gil Castro, António Gil Castro, Carmen Fernández, Anna-Lena Spetz, Lucille Adam, Moisés López González, Mahavir Singh, Rajko Reljic, África González-Fernández, África González-Fernández
Published 2021-01-01

Interleukin-6 Is a Biomarker for the Development of Fatal Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia

by André Santa Cruz, André Santa Cruz, André Santa Cruz, Ana Mendes-Frias, Ana Mendes-Frias, Ana Isabel Oliveira, Luís Dias, Luís Dias, Luís Dias, Ana Rita Matos, Alexandre Carvalho, Alexandre Carvalho, Alexandre Carvalho, Carlos Capela, Carlos Capela, Carlos Capela, Jorge Pedrosa, Jorge Pedrosa, António Gil Castro, António Gil Castro, Ricardo Silvestre, Ricardo Silvestre
Published 2021-02-01

Poor immune reconstitution in HIV-infected patients associates with high percentage of regulatory CD4+ T cells.

by Ana Horta, Claudia Nobrega, Pedro Amorim-Machado, Vitor Coutinho-Teixeira, Palmira Barreira-Silva, Susana Boavida, Patrício Costa, Rui Sarmento-Castro, António Gil Castro, Margarida Correia-Neves
Published 2013-01-01

The Dynamics of Interleukin-10-Afforded Protection during Dextran Sulfate Sodium-Induced Colitis

by Ana Cardoso, Ana Cardoso, Ana Cardoso, Ana Cardoso, Ana Cardoso, Ana Cardoso, Ana Cardoso, Antonio Gil Castro, Antonio Gil Castro, Ana Catarina Martins, Ana Catarina Martins, Guilhermina M. Carriche, Guilhermina M. Carriche, Valentine Murigneux, Valentine Murigneux, Isabel Castro, Isabel Castro, Ana Cumano, Ana Cumano, Ana Cumano, Paulo Vieira, Paulo Vieira, Paulo Vieira, Margarida Saraiva, Margarida Saraiva
Published 2018-03-01

Dysregulation of glycerophospholipid metabolism during Behçet’s disease contributes to a pro-inflammatory phenotype of circulating monocytes

by Ana Mendes-Frias, Bruno Santos-Lima, Danielle Zildeana Sousa Furtado, Francisco J. Ruperez, Nilson Antonio Assunção, Maria João Matias, Vânia Gomes, Joana Gaifem, Coral Barbas, António Gil Castro, Carlos Capela, Ricardo Silvestre
Published 2020-01-01

TLR9 activation dampens the early inflammatory response to Paracoccidioides brasiliensis, impacting host survival.

by João Filipe Menino, Margarida Saraiva, Ana G Gomes-Alves, Diogo Lobo-Silva, Mark Sturme, Jéssica Gomes-Rezende, Ana Laura Saraiva, Gustavo H Goldman, Cristina Cunha, Agostinho Carvalho, Luigina Romani, Jorge Pedrosa, António Gil Castro, Fernando Rodrigues
Published 2013-01-01

IL-17A promotes intracellular growth of Mycobacterium by inhibiting apoptosis of infected macrophages

by Andrea eCruz, Paula eLudovico, Egidio eTorrado, José Bernardo Gama, Jeremy eSousa, Joana eGaifem, Rui eAppelberg, Fernando eRodrigues, Andrea M Cooper, Jorge ePedrosa, Margarida eSaraiva, António Gil Castro
Published 2015-09-01

Correction: A Prediction Rule to Stratify Mortality Risk of Patients with Pulmonary Tuberculosis.

by Helder Novais Bastos, Nuno S Osório, António Gil Castro, Angélica Ramos, Teresa Carvalho, Leonor Meira, David Araújo, Leonor Almeida, Rita Boaventura, Patrícia Fragata, Catarina Chaves, Patrício Costa, Miguel Portela, Ivo Ferreira, Sara Pinto Magalhães, Fernando Rodrigues, Rui Sarmento Castro, Raquel Duarte, João Tiago Guimarães, Margarida Saraiva
Published 2020-01-01

A Prediction Rule to Stratify Mortality Risk of Patients with Pulmonary Tuberculosis.

by Helder Novais Bastos, Nuno S Osório, António Gil Castro, Angélica Ramos, Teresa Carvalho, Leonor Meira, David Araújo, Leonor Almeida, Rita Boaventura, Patrícia Fragata, Catarina Chaves, Patrício Costa, Miguel Portela, Ivo Ferreira, Sara Pinto Magalhães, Fernando Rodrigues, Rui Sarmento-Castro, Raquel Duarte, João Tiago Guimarães, Margarida Saraiva
Published 2016-01-01

The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis

by Inês Mesquita, Carolina Ferreira, Diana Moreira, George Eduardo Gabriel Kluck, Ana Margarida Barbosa, Egídio Torrado, Ricardo Jorge Dinis-Oliveira, Luís Gafeira Gonçalves, Charles-Joly Beauparlant, Arnaud Droit, Luciana Berod, Tim Sparwasser, Neelam Bodhale, Bhaskar Saha, Fernando Rodrigues, Cristina Cunha, Agostinho Carvalho, António Gil Castro, Jérôme Estaquier, Ricardo Silvestre
Published 2020-03-01

Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1β production

by Jeremy Sousa, Baltazar Cá, Ana Raquel Maceiras, Luisa Simões-Costa, Kaori L. Fonseca, Ana Isabel Fernandes, Angélica Ramos, Teresa Carvalho, Leandro Barros, Carlos Magalhães, Álvaro Chiner-Oms, Henrique Machado, Maria Isabel Veiga, Albel Singh, Rui Pereira, António Amorim, Jorge Vieira, Cristina P. Vieira, Apoorva Bhatt, Fernando Rodrigues, Pedro N. S. Rodrigues, Sebastien Gagneux, António Gil Castro, João Tiago Guimarães, Helder Novais Bastos, Nuno S. Osório, Iñaki Comas, Margarida Saraiva
Published 2020-04-01