RFamide Peptides: Structure, Function, Mechanisms and Pharmaceutical Potential

by Maria Findeisen, Annette G. Beck-Sickinger, Daniel Rathmann
Published 2011-09-01

Automated solid-phase peptide synthesis to obtain therapeutic peptides

by Veronika Mäde, Sylvia Els-Heindl, Annette G. Beck-Sickinger
Published 2014-05-01

Peptide-Drug Conjugates and Their Targets in Advanced Cancer Therapies

by Paul Hoppenz, Sylvia Els-Heindl, Annette G. Beck-Sickinger
Published 2020-07-01

Cell-Free Expression and Photo-Crosslinking of the Human Neuropeptide Y2 Receptor

by Lisa Maria Kögler, Jan Stichel, Anette Kaiser, Annette G. Beck-Sickinger
Published 2019-03-01

Neuropeptide Y receptors: How to get subtype selectivity

by Xavier ePedragosa Badia, Jan eStichel, Annette G Beck-Sickinger
Published 2013-02-01

Unusually persistent Gαi-signaling of the neuropeptide Y2 receptor depletes cellular Gi/o pools and leads to a Gi-refractory state

by Isabelle Ziffert, Anette Kaiser, Stefanie Babilon, Karin Mörl, Annette G. Beck-Sickinger
Published 2020-03-01

Characterisation of Neuropeptide Y Receptor Subtypes by Synthetic NPY Analogues and by Anti-receptor Antibodies

by Annette G. Beck-Sickinger, Heike A. Wieland, Chiara Cabrele, Christophe P. Eckard
Published 2001-04-01

NPY1R-targeted peptide-mediated delivery of a dual PPARα/γ agonist to adipocytes enhances adipogenesis and prevents diabetes progression

by Stefanie Wittrisch, Nora Klöting, Karin Mörl, Rima Chakaroun, Matthias Blüher, Annette G. Beck-Sickinger
Published 2020-01-01

Discovery of Small-Molecule Modulators of the Human Y4 Receptor.

by Gregory Sliwoski, Mario Schubert, Jan Stichel, David Weaver, Annette G Beck-Sickinger, Jens Meiler
Published 2016-01-01

Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes

by Catherine A. Tindall, Estelle Erkner, Jan Stichel, Annette G. Beck-Sickinger, Anne Hoffmann, Juliane Weiner, John T. Heiker
Published 2021-01-01

Cyclic Derivatives of the Chemerin C-Terminus as Metabolically Stable Agonists at the Chemokine-like Receptor 1 for Cancer Treatment

by Tobias F. Fischer, Anne S. Czerniak, Tina Weiß, Tristan Zellmann, Lina Zielke, Sylvia Els-Heindl, Annette G. Beck-Sickinger
Published 2021-07-01

Probing the Y₂ Receptor on Transmembrane, Intra- and Extra-Cellular Sites for EPR Measurements

by Jeannette M. Laugwitz, Haleh H. Haeri, Anette Kaiser, Ulrike Krug, Dariush Hinderberger, Annette G. Beck-Sickinger, Peter Schmidt
Published 2020-09-01

Integrating solid-state NMR and computational modeling to investigate the structure and dynamics of membrane-associated ghrelin.

by Gerrit Vortmeier, Stephanie H DeLuca, Sylvia Els-Heindl, Constance Chollet, Holger A Scheidt, Annette G Beck-Sickinger, Jens Meiler, Daniel Huster
Published 2015-01-01

An MRM-Based Multiplexed Quantification Assay for Human Adipokines and Apolipoproteins

by Laura Krieg, Alexandra Schaffert, Matthias Kern, Kathrin Landgraf, Martin Wabitsch, Annette G. Beck-Sickinger, Antje Körner, Matthias Blüher, Martin von Bergen, Kristin Schubert
Published 2020-02-01

The Dynamics of the Neuropeptide Y Receptor Type 1 Investigated by Solid-State NMR and Molecular Dynamics Simulation

by Alexander Vogel, Mathias Bosse, Marcel Gauglitz, Sarah Wistuba, Peter Schmidt, Anette Kaiser, Vsevolod V. Gurevich, Annette G. Beck-Sickinger, Peter W. Hildebrand, Daniel Huster
Published 2020-11-01

Development of Fluorinated Non-Peptidic Ghrelin Receptor Ligands for Potential Use in Molecular Imaging

by Rareş-Petru Moldovan, Sylvia Els-Heindl, Dennis J. Worm, Torsten Kniess, Michael Kluge, Annette G. Beck-Sickinger, Winnie Deuther-Conrad, Ute Krügel, Peter Brust
Published 2017-04-01

Design, synthesis, and biological evaluation of a multifunctional neuropeptide-Y conjugate for selective nuclear delivery of radiolanthanides

by Adrien Chastel, Dennis J. Worm, Isabel D. Alves, Delphine Vimont, Melina Petrel, Samantha Fernandez, Philippe Garrigue, Philippe Fernandez, Elif Hindié, Annette G. Beck-Sickinger, Clément Morgat
Published 2020-03-01

Central nervous system neuropeptide Y regulates mediators of hepatic phospholipid remodeling and very low-density lipoprotein triglyceride secretion via sympathetic innervation

by Jennifer M. Rojas, Eveline Bruinstroop, Richard L. Printz, Aldijana Alijagic-Boers, Ewout Foppen, Maxine K. Turney, Leena George, Annette G. Beck-Sickinger, Andries Kalsbeek, Kevin D. Niswender
Published 2015-03-01

The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion.

by Robert Spinnler, Theresa Gorski, Katharina Stolz, Susanne Schuster, Antje Garten, Annette G Beck-Sickinger, Marten A Engelse, Eelco J P de Koning, Antje Körner, Wieland Kiess, Kathrin Maedler
Published 2013-01-01

Improved in Vitro Folding of the Y2 G Protein-Coupled Receptor into Bicelles

by Peter Schmidt, Brian J. Bender, Brian J. Bender, Anette Kaiser, Khushboo Gulati, Holger A. Scheidt, Heidi E. Hamm, Jens Meiler, Jens Meiler, Annette G. Beck-Sickinger, Daniel Huster
Published 2018-01-01