A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation.

by Sahar Kassem, Guillaume Gaud, Isabelle Bernard, Mehdi Benamar, Anne S Dejean, Roland Liblau, Gilbert J Fournié, Céline Colacios, Bernard Malissen, Abdelhadi Saoudi
Published 2016-07-01

A spontaneous mutation of the rat Themis gene leads to impaired function of regulatory T cells linked to inflammatory bowel disease.

by Marianne Chabod, Christophe Pedros, Lucille Lamouroux, Céline Colacios, Isabelle Bernard, Dominique Lagrange, Daniela Balz-Hara, Jean-Francois Mosnier, Christian Laboisse, Nathalie Vergnolle, Olivier Andreoletti, Marie-Paule Roth, Roland Liblau, Gilbert J Fournié, Abdelhadi Saoudi, Anne S Dejean
Published 2012-01-01