Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization against PARP1 Inhibition in a Replication-Dependent Manner

by Johanna Rieckhoff, Felix Meyer, Sandra Classen, Alexandra Zielinski, Britta Riepen, Harriet Wikman, Cordula Petersen, Kai Rothkamm, Kerstin Borgmann, Ann Christin Parplys
Published 2020-09-01

Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer

by Felix Meyer, Saskia Becker, Sandra Classen, Ann Christin Parplys, Wael Yassin Mansour, Britta Riepen, Sara Timm, Claudia Ruebe, Maria Jasin, Harriet Wikman, Cordula Petersen, Kai Rothkamm, Kerstin Borgmann
Published 2020-01-01