Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice

by Chelsea Hepler, Mengle Shao, Jonathan Y Xia, Alexandra L Ghaben, Mackenzie J Pearson, Lavanya Vishvanath, Ankit X Sharma, Thomas S Morley, William L Holland, Rana K Gupta
Published 2017-07-01

Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis

by William L. Holland, Jonathan Y. Xia, Joshua A. Johnson, Kai Sun, Mackenzie J. Pearson, Ankit X. Sharma, Ezekiel Quittner-Strom, Trevor S. Tippetts, Ruth Gordillo, Philipp E. Scherer
Published 2017-03-01

De novo adipocyte differentiation from Pdgfrβ+ preadipocytes protects against pathologic visceral adipose expansion in obesity

by Mengle Shao, Lavanya Vishvanath, Napoleon C. Busbuso, Chelsea Hepler, Bo Shan, Ankit X. Sharma, Shiuhwei Chen, Xinxin Yu, Yu A. An, Yi Zhu, William L. Holland, Rana K. Gupta
Published 2018-03-01

Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice

by Ankit X. Sharma, Ezekiel B. Quittner-Strom, Young Lee, Joshua A. Johnson, Sarah A. Martin, Xinxin Yu, Jianping Li, John Lu, Zheqing Cai, Shiuhwei Chen, May-yun Wang, Yiyi Zhang, Mackenzie J. Pearson, Andie C. Dorn, Jeffrey G. McDonald, Ruth Gordillo, Hai Yan, Dung Thai, Zhao V. Wang, Roger H. Unger, William L. Holland
Published 2018-02-01