ATP as a Multi-target Danger Signal in the Brain

by Ricardo J Rodrigues, Angelo R Tomé, Angelo R Tomé, Rodrigo A Cunha, Rodrigo A Cunha
Published 2015-04-01

Validation of an LC-MS/MS Method for the Quantification of Caffeine and Theobromine Using Non-Matched Matrix Calibration Curve

by Vera M. Mendes, Margarida Coelho, Angelo R. Tomé, Rodrigo A. Cunha, Bruno Manadas
Published 2019-08-01

Crosstalk Between ATP-P2X7 and Adenosine A2A Receptors Controlling Neuroinflammation in Rats Subject to Repeated Restraint Stress

by Liliana Dias, Cátia R. Lopes, Francisco Q. Gonçalves, Ana Nunes, Daniela Pochmann, Nuno J. Machado, Angelo R. Tomé, Angelo R. Tomé, Paula Agostinho, Paula Agostinho, Rodrigo A. Cunha, Rodrigo A. Cunha
Published 2021-03-01

Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndrome

by Ana Moreira-de-Sá, Francisco Q. Gonçalves, João P. Lopes, Henrique B. Silva, Ângelo R. Tomé, Rodrigo A. Cunha, Paula M. Canas
Published 2020-12-01

Nicotinic α7 receptor activation selectively potentiates the function of NMDA receptors in glutamatergic terminals of the nucleus accumbens

by Stefania eZappettini, Massimo eGrilli, Guendalina eOlivero, Jiayang eChen, Cristina ePadolecchia, Anna ePittaluga, Angelo R Tomé, Rodrigo A Cunha, Mario eMarchi
Published 2014-10-01

Increased ATP release and CD73-mediated adenosine A2A receptor activation mediate convulsion-associated neuronal damage and hippocampal dysfunction

by Elisabete Augusto, Francisco Q. Gonçalves, Joana E. Real, Henrique B. Silva, Daniela Pochmann, Tiago S. Silva, Marco Matos, Nélio Gonçalves, Ângelo R. Tomé, Jiang-Fan Chen, Paula M. Canas, Rodrigo A. Cunha
Published 2021-09-01

Behavioral phenotyping of Parkin-deficient mice: looking for early preclinical features of Parkinson's disease.

by Daniel Rial, Adalberto A Castro, Nuno Machado, Pedro Garção, Francisco Q Gonçalves, Henrique B Silva, Angelo R Tomé, Attila Köfalvi, Olga Corti, Rita Raisman-Vozari, Rodrigo A Cunha, Rui D Prediger
Published 2014-01-01

Inactivation of adenosine A2A receptors reverses working memory deficits at early stages of Huntington's disease models

by Wei Li, Henrique B. Silva, Joana Real, Yu-Mei Wang, Daniel Rial, Ping Li, Marie-Pierce Payen, Yuanguo Zhou, Christa E. Muller, Angelo R. Tomé, Rodrigo A. Cunha, Jiang-Fan Chen
Published 2015-07-01

Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slices

by Mara Yone D. Fernandes, Fernando Dobrachinski, Henrique B. Silva, João Pedro Lopes, Francisco Q. Gonçalves, Felix A. A. Soares, Lisiane O. Porciúncula, Geanne M. Andrade, Rodrigo A. Cunha, Angelo R. Tomé
Published 2021-05-01

Synaptic and memory dysfunction in a β-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine

by Francisco Q. Gonçalves, João P. Lopes, Henrique B. Silva, Cristina Lemos, António C. Silva, Nélio Gonçalves, Ângelo R. Tomé, Samira G. Ferreira, Paula M. Canas, Daniel Rial, Paula Agostinho, Rodrigo A. Cunha
Published 2019-12-01