Shiga Toxin Type 2dact Displays Increased Binding to Globotriaosylceramide in vitro and Increased Lethality in Mice after Activation by Elastase

by Alison D. O'Brien, Angela R. Melton-Celsa, Joshua C. Bunger
Published 2013-11-01

Reduced Toxicity of Shiga Toxin (Stx) Type 2c in Mice Compared to Stx2d Is Associated with Instability of Stx2c Holotoxin

by Joshua C. Bunger, Angela R. Melton-Celsa, Ernest L. Maynard, Alison D. O'Brien
Published 2015-06-01

Comparisons of native Shiga toxins (Stxs) type 1 and 2 with chimeric toxins indicate that the source of the binding subunit dictates degree of toxicity.

by Lisa M Russo, Angela R Melton-Celsa, Michael J Smith, Alison D O'Brien
Published 2014-01-01

Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing <i>Escherichia coli</i> (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice

by Beth A. McNichol, Rebecca A. Bova, Kieron Torres, Lan N. Preston, Angela R. Melton-Celsa
Published 2021-01-01

Clinical Isolates of Shiga Toxin 1a–Producing Shigella flexneri with an Epidemiological Link to Recent Travel to Hispañiola

by Miranda D. Gray, Keith A. Lampel, Nancy A. Strockbine, Reinaldo E. Fernandez, Angela R. Melton-Celsa, Anthony T. Maurelli
Published 2014-10-01

Ricin crosses polarized human intestinal cells and intestines of ricin-gavaged mice without evident damage and then disseminates to mouse kidneys.

by Alyssa D Flora, Louise D Teel, Mark A Smith, James F Sinclair, Angela R Melton-Celsa, Alison D O'Brien
Published 2013-01-01

The Virulence of Escherichia coli O157:H7 Isolates in Mice Depends on Shiga Toxin Type 2a (Stx2a)-Induction and High Levels of Stx2a in Stool

by Jocelyn R. Hauser, Rama R. Atitkar, Courtney D. Petro, Rebecca L. Lindsey, Nancy Strockbine, Alison D. O'Brien, Angela R. Melton-Celsa
Published 2020-02-01

The Role of the AggR Regulon in the Virulence of the Shiga Toxin-Producing Enteroaggregative Escherichia coli Epidemic O104:H4 Strain in Mice

by Nadia Boisen, Nadia Boisen, Angela R. Melton-Celsa, Anne-Marie Hansen, Tonia Zangari, Mark A. Smith, Lisa M. Russo, Flemming Scheutz, Alison D. O’Brien, James P. Nataro, James P. Nataro
Published 2019-08-01

Genetic and Virulence Profiles of Enteroaggregative Escherichia coli (EAEC) Isolated From Deployed Military Personnel (DMP) With Travelers' Diarrhea

by Courtney D. Petro, Jeffrey K. Duncan, Yuliya I. Seldina, Anna Allué-Guardia, Anna Allué-Guardia, Mark Eppinger, Mark Eppinger, Mark S. Riddle, David R. Tribble, Ryan C. Johnson, Clifton L. Dalgard, Clifton L. Dalgard, Gauthaman Sukumar, Gauthaman Sukumar, Patrick Connor, Nadia Boisen, Angela R. Melton-Celsa
Published 2020-05-01