Mitochondrial Calcium Deregulation in the Mechanism of Beta-Amyloid and Tau Pathology

by Noemi Esteras, Andrey Y. Abramov
Published 2020-09-01

Mechanism of Oxidative Stress in Neurodegeneration

by Sonia Gandhi, Andrey Y. Abramov
Published 2012-01-01

Genetically engineered MAPT 10+16 mutation causes pathophysiological excitability of human iPSC-derived neurons related to 4R tau-induced dementia

by Olga Kopach, Noemí Esteras, Selina Wray, Andrey Y. Abramov, Dmitri A. Rusakov
Published 2021-07-01

Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration

by Noemí Esteras, Jonathan D. Rohrer, John Hardy, Selina Wray, Andrey Y. Abramov
Published 2017-08-01

Interaction of Oxidative Stress and Misfolded Proteins in the Mechanism of Neurodegeneration

by Andrey Y. Abramov, Elena V. Potapova, Viktor V. Dremin, Andrey V. Dunaev
Published 2020-06-01

Dopamine induced neurodegeneration in a PINK1 model of Parkinson's disease.

by Sonia Gandhi, Annika Vaarmann, Zhi Yao, Michael R Duchen, Nicholas W Wood, Andrey Y Abramov
Published 2012-01-01

Polyhydroxybutyrate targets mammalian mitochondria and increases permeability of plasmalemmal and mitochondrial membranes.

by Pia A Elustondo, Plamena R Angelova, Michał Kawalec, Michał Michalak, Piotr Kurcok, Andrey Y Abramov, Evgeny V Pavlov
Published 2013-01-01

Combination antioxidant therapy prevents epileptogenesis and modifies chronic epilepsy

by Tawfeeq Shekh-Ahmad, Andreas Lieb, Stjepana Kovac, Lukas Gola, W. Christian Wigley, Andrey Y. Abramov, Matthew C. Walker
Published 2019-09-01

Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes.

by Natalia Igosheva, Andrey Y Abramov, Lucilla Poston, Judith J Eckert, Tom P Fleming, Michael R Duchen, Josie McConnell
Published 2010-04-01

PKA Phosphorylation of NCLX Reverses Mitochondrial Calcium Overload and Depolarization, Promoting Survival of PINK1-Deficient Dopaminergic Neurons

by Marko Kostic, Marthe H.R. Ludtmann, Hilmar Bading, Michal Hershfinkel, Erin Steer, Charleen T. Chu, Andrey Y. Abramov, Israel Sekler
Published 2015-10-01

PINK1 deficiency in β-cells increases basal insulin secretion and improves glucose tolerance in mice

by Emma Deas, Kaisa Piipari, Asif Machhada, Abi Li, Ana Gutierrez-del-Arroyo, Dominic J. Withers, Nicholas W. Wood, Andrey Y. Abramov
Published 2014-01-01

Hereditary sensory neuropathy type 1-associated deoxysphingolipids cause neurotoxicity, acute calcium handling abnormalities and mitochondrial dysfunction in vitro

by Emma R. Wilson, Umaiyal Kugathasan, Andrey Y. Abramov, Alex J. Clark, David L.H. Bennett, Mary M. Reilly, Linda Greensmith, Bernadett Kalmar
Published 2018-09-01

Proteomic Analysis of Cardiac Adaptation to Exercise by High Resolution Mass Spectrometry

by Afnan Saleh Al-Menhali, Afnan Saleh Al-Menhali, Cali Anderson, Alexander V. Gourine, Andrey Y. Abramov, Alicia D’Souza, Morana Jaganjac, Morana Jaganjac
Published 2021-09-01

Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration

by Kira M. Holmström, Liam Baird, Ying Zhang, Iain Hargreaves, Annapurna Chalasani, John M. Land, Lee Stanyer, Masayuki Yamamoto, Albena T. Dinkova-Kostova, Andrey Y. Abramov
Published 2013-06-01

Mitochondrial dysfunction in Parkinsonian mesenchymal stem cells impairs differentiation

by Plamena R. Angelova, Mario Barilani, Christopher Lovejoy, Marta Dossena, Mariele Viganò, Agostino Seresini, Daniela Piga, Sonia Gandhi, Gianni Pezzoli, Andrey Y. Abramov, Lorenza Lazzari
Published 2018-04-01

Synthetic Fragments of Receptor for Advanced Glycation End Products Bind Beta-Amyloid 1–40 and Protect Primary Brain Cells From Beta-Amyloid Toxicity

by Anna V. Kamynina, Noemi Esteras, Dmitriy O. Koroev, Natalia V. Bobkova, Samson M. Balasanyants, Ruben A. Simonyan, Armine V. Avetisyan, Andrey Y. Abramov, Olga M. Volpina
Published 2018-09-01

Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates

by Fernando Bartolome, Noemi Esteras, Angeles Martin-Requero, Claire Boutoleau-Bretonniere, Martine Vercelletto, Audrey Gabelle, Isabelle Le Ber, Tadashi Honda, Albena T. Dinkova-Kostova, John Hardy, Eva Carro, Andrey Y. Abramov
Published 2017-05-01

iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease.

by Charles Arber, Plamena R Angelova, Sarah Wiethoff, Yugo Tsuchiya, Francesca Mazzacuva, Elisavet Preza, Kailash P Bhatia, Kevin Mills, Ivan Gout, Andrey Y Abramov, John Hardy, James A Duce, Henry Houlden, Selina Wray
Published 2017-01-01

Correction: PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons

by Alison Wood-Kaczmar, Sonia Gandhi, Zhi Yao, Andrey Y. Abramov, Erik A. Miljan, Gregory Keen, Lee Stanyer, Iain Hargreaves, Kristina Klupsch, Emma Deas, Julian Downward, Louise Mansfield, Parmjit Jat, Joanne Taylor, Simon Heales, Michael R. Duchen, David Latchman, Sarah J. Tabrizi, Nicholas W. Wood
Published 2008-01-01

Correction: PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons

by Alison Wood-Kaczmar, Sonia Gandhi, Zhi Yao, Andrey Y. Abramov, Erik A. Miljan, Gregory Keen, Lee Stanyer, Iain Hargreaves, Kristina Klupsch, Emma Deas, Julian Downward, Louise Mansfield, Parmjit Jat, Joanne Taylor, Simon Heales, Michael R. Duchen, David Latchman, Sarah J. Tabrizi, Nicholas W. Wood
Published 2008-01-01