Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

by Paul RHJ Timmers, Ninon Mounier, Kristi Lall, Krista Fischer, Zheng Ning, Xiao Feng, Andrew D Bretherick, David W Clark, eQTLGen Consortium, Xia Shen, Tõnu Esko, Zoltán Kutalik, James F Wilson, Peter K Joshi
Published 2019-01-01

Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles

by Rosie M. Walker, Kadi Vaher, Mairead L. Bermingham, Stewart W. Morris, Andrew D. Bretherick, Yanni Zeng, Konrad Rawlik, Carmen Amador, Archie Campbell, Chris S. Haley, Caroline Hayward, David J. Porteous, Andrew M. McIntosh, Riccardo E. Marioni, Kathryn L. Evans
Published 2021-01-01

Epigenome‐wide analyses identify DNA methylation signatures of dementia risk

by Rosie M. Walker, Mairead L. Bermingham, Kadi Vaher, Stewart W. Morris, Toni‐Kim Clarke, Andrew D. Bretherick, Yanni Zeng, Carmen Amador, Konrad Rawlik, Kalyani Pandya, Caroline Hayward, Archie Campbell, David J. Porteous, Andrew M. McIntosh, Riccardo E. Marioni, Kathryn L. Evans
Published 2020-01-01

Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits.

by Andrew D Bretherick, Oriol Canela-Xandri, Peter K Joshi, David W Clark, Konrad Rawlik, Thibaud S Boutin, Yanni Zeng, Carmen Amador, Pau Navarro, Igor Rudan, Alan F Wright, Harry Campbell, Veronique Vitart, Caroline Hayward, James F Wilson, Albert Tenesa, Chris P Ponting, J Kenneth Baillie, Chris Haley
Published 2020-07-01