Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis

by Elizabeth R. Morris, Sarah J. Caswell, Simone Kunzelmann, Laurence H. Arnold, Andrew G. Purkiss, Geoff Kelly, Ian A. Taylor
Published 2020-06-01

Mutations in SKI in Shprintzen–Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization

by Ilaria Gori, Roger George, Andrew G Purkiss, Stephanie Strohbuecker, Rebecca A Randall, Roksana Ogrodowicz, Virginie Carmignac, Laurence Faivre, Dhira Joshi, Svend Kjær, Caroline S Hill
Published 2021-01-01

RET Recognition of GDNF-GFRα1 Ligand by a Composite Binding Site Promotes Membrane-Proximal Self-Association

by Kerry M. Goodman, Svend Kjær, Fabienne Beuron, Phillip P. Knowles, Agata Nawrotek, Emily M. Burns, Andrew G. Purkiss, Roger George, Massimo Santoro, Edward P. Morris, Neil Q. McDonald
Published 2014-09-01

Structure of the cohesin loader Scc2

by William C. H. Chao, Yasuto Murayama, Sofía Muñoz, Andrew W. Jones, Benjamin O. Wade, Andrew G. Purkiss, Xiao-Wen Hu, Aaron Borg, Ambrosius P. Snijders, Frank Uhlmann, Martin R. Singleton
Published 2017-01-01