Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation

by Matthew Y. Tang, Marta Vranas, Andrea I. Krahn, Shayal Pundlik, Jean- François Trempe, Edward A. Fon
Published 2017-03-01

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

by Gian-Luca McLelland, Thomas Goiran, Wei Yi, Geneviève Dorval, Carol X Chen, Nadine D Lauinger, Andrea I Krahn, Sepideh Valimehr, Aleksandar Rakovic, Isabelle Rouiller, Thomas M Durcan, Jean-François Trempe, Edward A Fon
Published 2018-04-01