Machine learning uncovers independently regulated modules in the Bacillus subtilis transcriptome

by Kevin Rychel, Anand V. Sastry, Bernhard O. Palsson
Published 2020-12-01

Independent component analysis recovers consistent regulatory signals from disparate datasets.

by Anand V Sastry, Alyssa Hu, David Heckmann, Saugat Poudel, Erol Kavvas, Bernhard O Palsson
Published 2021-02-01

Restoration of fitness lost due to dysregulation of the pyruvate dehydrogenase complex is triggered by ribosomal binding site modifications

by Amitesh Anand, Connor A. Olson, Anand V. Sastry, Arjun Patel, Richard Szubin, Laurence Yang, Adam M. Feist, Bernhard O. Palsson
Published 2021-04-01

Machine Learning of Bacterial Transcriptomes Reveals Responses Underlying Differential Antibiotic Susceptibility

by Anand V. Sastry, Nicholas Dillon, Amitesh Anand, Saugat Poudel, Ying Hefner, Sibei Xu, Richard Szubin, Adam M. Feist, Victor Nizet, Bernhard Palsson
Published 2021-08-01

The Escherichia coli transcriptome mostly consists of independently regulated modules

by Anand V. Sastry, Ye Gao, Richard Szubin, Ying Hefner, Sibei Xu, Donghyuk Kim, Kumari Sonal Choudhary, Laurence Yang, Zachary A. King, Bernhard O. Palsson
Published 2019-12-01

BOFdat: Generating biomass objective functions for genome-scale metabolic models from experimental data.

by Jean-Christophe Lachance, Colton J Lloyd, Jonathan M Monk, Laurence Yang, Anand V Sastry, Yara Seif, Bernhard O Palsson, Sébastien Rodrigue, Adam M Feist, Zachary A King, Pierre-Étienne Jacques
Published 2019-04-01