Polygenic Score Models for Alzheimer’s Disease: From Research to Clinical Applications

by Xiaopu Zhou, Xiaopu Zhou, Xiaopu Zhou, Yolanda Y. T. Li, Amy K. Y. Fu, Amy K. Y. Fu, Amy K. Y. Fu, Nancy Y. Ip, Nancy Y. Ip, Nancy Y. Ip
Published 2021-03-01

Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer’s disease mouse model

by Shun-Fat Lau, Wei Wu, Heukjin Seo, Amy K.Y. Fu, Nancy Y. Ip
Published 2021-03-01

Stimulation of the Hippocampal POMC/MC4R Circuit Alleviates Synaptic Plasticity Impairment in an Alzheimer’s Disease Model

by Yang Shen, Min Tian, Yuqiong Zheng, Fei Gong, Amy K.Y. Fu, Nancy Y. Ip
Published 2016-11-01

Cdk5 Phosphorylates a Component of the HDAC Complex and Regulates Histone Acetylation during Neuronal Cell Death

by Amy K.Y. Fu, Kwok-Wang Hung, Hovy Ho-Wai Wong, Wing-Yu Fu, Nancy Y. Ip
Published 2012-03-01

p35 regulates the CRM1-dependent nucleocytoplasmic shuttling of nuclear hormone receptor coregulator-interacting factor 1 (NIF-1).

by Xiao-Su Zhao, Wing-Yu Fu, Winnie W Y Chien, Zhen Li, Amy K Y Fu, Nancy Y Ip
Published 2014-01-01

Overproduction of Upper-Layer Neurons in the Neocortex Leads to Autism-like Features in Mice

by Wei-Qun Fang, Wei-Wei Chen, Liwen Jiang, Kai Liu, Wing-Ho Yung, Amy K.Y. Fu, Nancy Y. Ip
Published 2014-12-01

Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer’s disease transgenic mouse model

by Jackie K. Y. Lau, Min Tian, Yang Shen, Shun-Fat Lau, Wing-Yu Fu, Amy K. Y. Fu, Nancy Y. Ip
Published 2021-02-01

IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer’s Disease

by Shun-Fat Lau, Congping Chen, Wing-Yu Fu, Jianan Y. Qu, Tom H. Cheung, Amy K.Y. Fu, Nancy Y. Ip
Published 2020-04-01

Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases

by Tao Ye, Yangyang Duan, Hayley W. S. Tsang, He Xu, Yuewen Chen, Han Cao, Yu Chen, Amy K. Y. Fu, Nancy Y. Ip
Published 2021-02-01

Identification of new EphA4 inhibitors by virtual screening of FDA-approved drugs

by Shuo Gu, Wing-Yu Fu, Amy K. Y. Fu, Estella Pui Sze Tong, Fanny C. F. Ip, Xuhui Huang, Nancy Y. Ip
Published 2018-05-01

Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling.

by Yu Chen, Zhuoyi Liang, Erkang Fei, Yuewen Chen, Xiaopu Zhou, Weiqun Fang, Wing-Yu Fu, Amy K Y Fu, Nancy Y Ip
Published 2015-01-01

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

by Xiaopu Zhou, Yu Chen, Kin Y. Mok, Timothy C. Y. Kwok, Vincent C. T. Mok, Qihao Guo, Fanny C. Ip, Yuewen Chen, Nandita Mullapudi, Alzheimer’s Disease Neuroimaging Initiative, Paola Giusti-Rodríguez, Patrick F. Sullivan, John Hardy, Amy K. Y. Fu, Yun Li, Nancy Y. Ip
Published 2019-07-01

Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population

by Xiaopu Zhou, Yu Chen, Fanny C. F. Ip, Nicole C. H. Lai, Yolanda Y. T. Li, Yuanbing Jiang, Huan Zhong, Yuewen Chen, Yulin Zhang, Shuangshuang Ma, Ronnie M. N. Lo, Kit Cheung, Estella P. S. Tong, Ho Ko, Maryam Shoai, Kin Y. Mok, John Hardy, Vincent C. T. Mok, Timothy C. Y. Kwok, Amy K. Y. Fu, Nancy Y. Ip
Published 2020-01-01