An in vitro co-culture mouse model demonstrates efficient vaccine-mediated control of Francisella tularensis SCHU S4 and identifies nitric oxide as a predictor of efficacy

by Igor Golovlev, Helena Lindgren, Kjell Eneslätt, Wayne Conlan, Amandine Mosnier, Thomas Henry, Anders Sjöstedt
Published 2016-11-01

Francisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins and Harbors a Unique N-terminal Extension Required for Virulence.

by Mélanie Rigard, Jeanette E Bröms, Amandine Mosnier, Maggy Hologne, Amandine Martin, Lena Lindgren, Claire Punginelli, Claire Lays, Olivier Walker, Alain Charbit, Philippe Telouk, Wayne Conlan, Laurent Terradot, Anders Sjöstedt, Thomas Henry
Published 2016-09-01

IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection.

by Pierre Wallet, Sacha Benaoudia, Amandine Mosnier, Brice Lagrange, Amandine Martin, Helena Lindgren, Igor Golovliov, Fanny Michal, Pauline Basso, Sophia Djebali, Angelina Provost, Omran Allatif, Etienne Meunier, Petr Broz, Masahiro Yamamoto, Bénédicte F Py, Eric Faudry, Anders Sjöstedt, Thomas Henry
Published 2017-10-01