Functional connections between cell cycle and proteostasis in the regulation of Candida albicans morphogenesis

by Saif Hossain, Emma Lash, Amanda O. Veri, Leah E. Cowen
Published 2021-02-01

Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress.

by Teresa R O'Meara, Amanda O Veri, Elizabeth J Polvi, Xinliu Li, Seyedeh Fereshteh Valaei, Stephanie Diezmann, Leah E Cowen
Published 2016-06-01

Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis.

by Elizabeth J Polvi, Anna F Averette, Soo Chan Lee, Taeyup Kim, Yong-Sun Bahn, Amanda O Veri, Nicole Robbins, Joseph Heitman, Leah E Cowen
Published 2016-10-01

Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1-Hsp90 pathway.

by Guobo Guan, Li Tao, Huizhen Yue, Weihong Liang, Jiao Gong, Jian Bing, Qiushi Zheng, Amanda O Veri, Shuru Fan, Nicole Robbins, Leah E Cowen, Guanghua Huang
Published 2019-03-01

The macrophage-derived protein PTMA induces filamentation of the human fungal pathogen Candida albicans

by Nicola T. Case, Kwamaa Duah, Brett Larsen, Cassandra J. Wong, Anne-Claude Gingras, Teresa R. O’Meara, Nicole Robbins, Amanda O. Veri, Luke Whitesell, Leah E. Cowen
Published 2021-08-01

Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fung...

by Teresa R O'Meara, Matthew J O'Meara, Elizabeth J Polvi, M Reza Pourhaghighi, Sean D Liston, Zhen-Yuan Lin, Amanda O Veri, Andrew Emili, Anne-Claude Gingras, Leah E Cowen
Published 2019-07-01

Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space.

by Amanda O Veri, Zhengqiang Miao, Rebecca S Shapiro, Faiza Tebbji, Teresa R O'Meara, Sang Hu Kim, Juan Colazo, Kaeling Tan, Valmik K Vyas, Malcolm Whiteway, Nicole Robbins, Koon Ho Wong, Leah E Cowen
Published 2018-03-01

Functional divergence of a global regulatory complex governing fungal filamentation.

by Elizabeth J Polvi, Amanda O Veri, Zhongle Liu, Saif Hossain, Sabrina Hyde, Sang Hu Kim, Faiza Tebbji, Adnane Sellam, Robert T Todd, Jinglin L Xie, Zhen-Yuan Lin, Cassandra J Wong, Rebecca S Shapiro, Malcolm Whiteway, Nicole Robbins, Anne-Claude Gingras, Anna Selmecki, Leah E Cowen
Published 2019-01-01

High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis

by Teresa R. O’Meara, Kwamaa Duah, Cynthia X. Guo, Michelle E. Maxson, Ryan G. Gaudet, Kristy Koselny, Melanie Wellington, Michael E. Powers, Jessie MacAlpine, Matthew J. O’Meara, Amanda O. Veri, Sergio Grinstein, Suzanne M. Noble, Damian Krysan, Scott D. Gray-Owen, Leah E. Cowen
Published 2018-08-01