Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk

by Anastasia G. Efthymiou, Alison M. Goate
Published 2017-05-01

Novel presenilin 1 and 2 double knock-out cell line for in vitro validation of PSEN1 and PSEN2 mutations

by Anna A. Pimenova, Alison M. Goate
Published 2020-05-01

Genetic architecture of Alzheimer's disease

by Sarah M. Neuner, Julia TCW, Alison M. Goate
Published 2020-09-01

Heterogeneous effects of genetic risk for Alzheimer’s disease on the phenome

by Hei Man Wu, Alison M. Goate, Paul F. O’Reilly
Published 2021-07-01

Reduced variability of neural progenitor cells and improved purity of neuronal cultures using magnetic activated cell sorting.

by Kathryn R Bowles, Julia Tcw, Lu Qian, Benjamin M Jadow, Alison M Goate
Published 2019-01-01

Mutations in APP have independent effects on Aβ and CTFγ generation

by Silva Hecimovic, Jun Wang, Georgia Dolios, Maribel Martinez, Rong Wang, Alison M. Goate
Published 2004-11-01

Expression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains.

by Celeste M Karch, Amanda T Jeng, Petra Nowotny, Janet Cady, Carlos Cruchaga, Alison M Goate
Published 2012-01-01

Functional characterization improves associations between rare non-synonymous variants in CHRNB4 and smoking behavior.

by Gabe Haller, Ping Li, Caroline Esch, Simon Hsu, Alison M Goate, Joe Henry Steinbach
Published 2014-01-01

Presenilins Upregulate Functional K+Channel Currents in Mammalian Cells

by Sacha A. Malin, W.-X.Athena Guo, Gita Jafari, Alison M. Goate, Jeanne M. Nerbonne
Published 1998-01-01

Generation of a gene-corrected human isogenic iPSC line from an Alzheimer’s disease iPSC line carrying the London mutation in APP (V717I)

by Damián Hernández, Stephanie Morgan Schlicht, Maciej Daniszewski, Celeste M. Karch, Alison M. Goate, Alice Pébay
Published 2021-05-01

Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.

by Celeste M Karch, Lubov A Ezerskiy, Sarah Bertelsen, Alzheimer’s Disease Genetics Consortium (ADGC), Alison M Goate
Published 2016-01-01

Alzheimer's-associated PU.1 expression levels regulate microglial inflammatory response

by Anna A. Pimenova, Manon Herbinet, Ishaan Gupta, Saima I. Machlovi, Kathryn R. Bowles, Edoardo Marcora, Alison M. Goate
Published 2021-01-01

Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2

by Simon Hsu, Anna A. Pimenova, Kimberly Hayes, Juan A. Villa, Matthew J. Rosene, Madhavi Jere, Alison M. Goate, Celeste M. Karch
Published 2020-06-01

Characterizing the role of brain derived neurotrophic factor genetic variation in Alzheimer's disease neurodegeneration.

by Robyn A Honea, Carlos Cruchaga, Rodrigo D Perea, Andrew J Saykin, Jeffrey M Burns, Daniel R Weinberger, Alison M Goate, Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Published 2013-01-01

Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels

by Taylor J. Maxwell, Chris Corcoran, Jorge L. del-Aguila, John P. Budde, Yuetiva Deming, Carlos Cruchaga, Alison M. Goate, John S. K. Kauwe, Alzheimer’s Disease Neuroimaging Initiative
Published 2018-08-01

Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques

by Pranav Preman, Julia TCW, Sara Calafate, An Snellinx, Maria Alfonso-Triguero, Nikky Corthout, Sebastian Munck, Dietmar Rudolf Thal, Alison M Goate, Bart De Strooper, Amaia M Arranz
Published 2021-09-01

Correction: Pathway Analysis of Smoking Quantity in Multiple GWAS Identifies Cholinergic and Sensory Pathways

by Oscar Harari, Jen-Chyong Wang, Kathleen Bucholz, Howard J. Edenberg, Andrew Heath, Nicholas G. Martin, Michele L. Pergadia, Grant Montgomery, Andrew Schrage, Laura J. Bierut, Pamela F. Madden, Alison M. Goate
Published 2013-01-01

Correction: Pathway Analysis of Smoking Quantity in Multiple GWAS Identifies Cholinergic and Sensory Pathways.

by Oscar Harari, Jen-Chyong Wang, Kathleen Bucholz, Howard J. Edenberg, Andrew Heath, Nicholas G. Martin, Michele L. Pergadia, Grant Montgomery, Andrew Schrage, Laura J. Bierut, Pamela F. Madden, Alison M. Goate
Published 2013-01-01

Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways.

by Oscar Harari, Jen-Chyong Wang, Kathleen Bucholz, Howard J Edenberg, Andrew Heath, Nicholas G Martin, Michele L Pergadia, Grant Montgomery, Andrew Schrage, Laura J Bierut, Pamela F Madden, Alison M Goate
Published 2012-01-01

A new statistic to evaluate imputation reliability.

by Peng Lin, Sarah M Hartz, Zhehao Zhang, Scott F Saccone, Jia Wang, Jay A Tischfield, Howard J Edenberg, John R Kramer, Alison M Goate, Laura J Bierut, John P Rice, COGA Collaborators COGEND Collaborators, GENEVA
Published 2010-03-01