CD14 is critical for TLR2-mediated M1 macrophage activation triggered by N-glycan recognition

by Thiago Aparecido da Silva, André L. V. Zorzetto-Fernandes, Nerry T. Cecílio, Aline Sardinha-Silva, Fabrício Freitas Fernandes, Maria Cristina Roque-Barreira
Published 2017-08-01

IL-17 Induction by ArtinM is Due to Stimulation of IL-23 and IL-1 Release and/or Interaction with CD3 in CD4+ T Cells.

by Thiago Aparecido da Silva, Vania Sammartino Mariano, Aline Sardinha-Silva, Maria Aparecida de Souza, Tiago Wilson Patriarca Mineo, Maria Cristina Roque-Barreira
Published 2016-01-01

Vaccination with Recombinant Microneme Proteins Confers Protection against Experimental Toxoplasmosis in Mice.

by Camila Figueiredo Pinzan, Aline Sardinha-Silva, Fausto Almeida, Livia Lai, Carla Duque Lopes, Elaine Vicente Lourenço, Ademilson Panunto-Castelo, Stephen Matthews, Maria Cristina Roque-Barreira
Published 2015-01-01

Receptor Heterodimerization and Co-Receptor Engagement in TLR2 Activation Induced by MIC1 and MIC4 from <em>Toxoplasma gondii</em>

by Flávia Costa Mendonça-Natividade, Carla Duque Lopes, Rafael Ricci-Azevedo, Aline Sardinha-Silva, Camila Figueiredo Pinzan, Ana Claudia Paiva Alegre-Maller, Lilian L. Nohara, Alan B. Carneiro, Ademilson Panunto-Castelo, Igor C. Almeida, Maria Cristina Roque-Barreira
Published 2019-10-01

The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming.

by Aline Sardinha-Silva, Flávia C Mendonça-Natividade, Camila F Pinzan, Carla D Lopes, Diego L Costa, Damien Jacot, Fabricio F Fernandes, André L V Zorzetto-Fernandes, Nicholas J Gay, Alan Sher, Dragana Jankovic, Dominique Soldati-Favre, Michael E Grigg, Maria Cristina Roque-Barreira
Published 2019-06-01

Toxoplasma gondii Chitinase Induces Macrophage Activation.

by Fausto Almeida, Aline Sardinha-Silva, Thiago Aparecido da Silva, André Moreira Pessoni, Camila Figueiredo Pinzan, Ana Claudia Paiva Alegre-Maller, Nerry Tatiana Cecílio, Nilmar Silvio Moretti, André Ricardo Lima Damásio, Wellington Ramos Pedersoli, José Roberto Mineo, Roberto Nascimento Silva, Maria Cristina Roque-Barreira
Published 2015-01-01