Commentary: Atrial Rotor Dynamics Under Complex Fractional Order Diffusion

by Alfonso Bueno-Orovio
Published 2018-10-01

Multiscale Modelling of β-Adrenergic Stimulation in Cardiac Electromechanical Function

by Ruben Doste, Alfonso Bueno-Orovio
Published 2021-07-01

Strategies of data layout and cache writing for input-output optimization in high performance scientific computing: Applications to the forward electrocardiographic problem.

by Louie Cardone-Noott, Blanca Rodriguez, Alfonso Bueno-Orovio
Published 2018-01-01

Dual Transcriptomic and Molecular Machine Learning Predicts all Major Clinical Forms of Drug Cardiotoxicity

by Polina Mamoshina, Polina Mamoshina, Alfonso Bueno-Orovio, Blanca Rodriguez
Published 2020-05-01

On the Order of the Fractional Laplacian in Determining the Spatio-Temporal Evolution of a Space-Fractional Model of Cardiac Electrophysiology.

by Nicole Cusimano, Alfonso Bueno-Orovio, Ian Turner, Kevin Burrage
Published 2015-01-01

Basis for the Induction of Tissue-Level Phase-2 Reentry as a Repolarization Disorder in the Brugada Syndrome

by Alfonso Bueno-Orovio, Elizabeth M. Cherry, Steven J. Evans, Flavio H. Fenton
Published 2015-01-01

The Electrogenic Na+/K+ Pump Is a Key Determinant of Repolarization Abnormality Susceptibility in Human Ventricular Cardiomyocytes: A Population-Based Simulation Study

by Oliver J. Britton, Alfonso Bueno-Orovio, László Virág, András Varró, Blanca Rodriguez
Published 2017-05-01

Corrigendum: The Electrogenic Na+/K+ Pump Is a Key Determinant of Repolarization Abnormality Susceptibility in Human Ventricular Cardiomyocytes: A Population-Based Simulation Study

by Oliver J. Britton, Alfonso Bueno-Orovio, László Virág, András Varró, Blanca Rodriguez
Published 2017-11-01

In vivo human left-to-right ventricular differences in rate adaptation transiently increase pro-arrhythmic risk following rate acceleration.

by Alfonso Bueno-Orovio, Ben M Hanson, Jaswinder S Gill, Peter Taggart, Blanca Rodriguez
Published 2012-01-01

Atrial Fibrillation Dynamics and Ionic Block Effects in Six Heterogeneous Human 3D Virtual Atria with Distinct Repolarization Dynamics

by Carlos Sánchez, Carlos Sánchez, Alfonso Bueno-Orovio, Esther Pueyo, Esther Pueyo, Blanca Rodríguez
Published 2017-05-01

Slow Recovery of Excitability Increases Ventricular Fibrillation Risk as Identified by Emulation

by Brodie A. Lawson, Kevin Burrage, Kevin Burrage, Pamela Burrage, Christopher C. Drovandi, Alfonso Bueno-Orovio
Published 2018-08-01

Blinded In Silico Drug Trial Reveals the Minimum Set of Ion Channels for Torsades de Pointes Risk Assessment

by Xin Zhou, Yusheng Qu, Elisa Passini, Alfonso Bueno-Orovio, Yang Liu, Hugo M. Vargas, Blanca Rodriguez
Published 2020-01-01

Inter-subject variability in human atrial action potential in sinus rhythm versus chronic atrial fibrillation.

by Carlos Sánchez, Alfonso Bueno-Orovio, Erich Wettwer, Simone Loose, Jana Simon, Ursula Ravens, Esther Pueyo, Blanca Rodriguez
Published 2014-01-01

Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity

by Elisa Passini, Oliver J. Britton, Hua Rong Lu, Jutta Rohrbacher, An N. Hermans, David J. Gallacher, Robert J. H. Greig, Alfonso Bueno-Orovio, Blanca Rodriguez
Published 2017-09-01

Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block

by Jakub Tomek, Alfonso Bueno-Orovio, Elisa Passini, Xin Zhou, Ana Minchole, Oliver Britton, Chiara Bartolucci, Stefano Severi, Alvin Shrier, Laszlo Virag, Andras Varro, Blanca Rodriguez
Published 2019-12-01

Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D

by Xin Zhou, Alfonso Bueno-Orovio, Richard J. Schilling, Claire Kirkby, Chris Denning, Divya Rajamohan, Kevin Burrage, Kevin Burrage, Kevin Burrage, Andrew Tinker, Blanca Rodriguez, Stephen C. Harmer
Published 2019-03-01

Electrophysiological and Contractile Effects of Disopyramide in Patients With Obstructive Hypertrophic Cardiomyopathy

by Raffaele Coppini, MD, PhD, Cecilia Ferrantini, MD, PhD, Josè Manuel Pioner, PhD, Lorenzo Santini, MS, Zhinuo J. Wang, PhD, Chiara Palandri, MS, Marina Scardigli, PhD, Giulia Vitale, MS, Leonardo Sacconi, PhD, Pierluigi Stefàno, MD, Laura Flink, MD, Katherine Riedy, MD, Francesco Saverio Pavone, PhD, Elisabetta Cerbai, PhD, Corrado Poggesi, MD, Alessandro Mugelli, MD, Alfonso Bueno-Orovio, PhD, Iacopo Olivotto, MD, Mark V. Sherrid, MD
Published 2019-11-01