Drosophila sperm swim backwards in the female reproductive tract and are activated via TRPP2 ion channels.

by Michael Köttgen, Alexis Hofherr, Weizhe Li, Kristy Chu, Stacey Cook, Craig Montell, Terry Watnick
Published 2011-01-01

Rapid target validation in a Cas9-inducible hiPSC derived kidney model

by Yasaman Shamshirgaran, Anna Jonebring, Anna Svensson, Isabelle Leefa, Mohammad Bohlooly-Y, Mike Firth, Kevin J. Woollard, Alexis Hofherr, Ian M. Rogers, Ryan Hicks
Published 2021-08-01

Identification of pathological transcription in autosomal dominant polycystic kidney disease epithelia

by Sebastian Friedrich, Hannah Müller, Caroline Riesterer, Hannah Schüller, Katja Friedrich, Carlotta Leonie Wörner, Tilman Busch, Amandine Viau, E. Wolfgang Kuehn, Michael Köttgen, Alexis Hofherr
Published 2021-07-01

Eomes cannot replace its paralog T-bet during expansion and differentiation of CD8 effector T cells.

by Jonas Fixemer, Jonas F Hummel, Frederic Arnold, Christoph S N Klose, Alexis Hofherr, Kristoffer Weissert, Tamara Kögl, Michael Köttgen, Sebastian J Arnold, Peter Aichele, Yakup Tanriver
Published 2020-09-01

The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism.

by Alexis Hofherr, Claudia Seger, Fiona Fitzpatrick, Tilman Busch, Elisabeth Michel, Jingting Luan, Lea Osterried, Frieder Linden, Albrecht Kramer-Zucker, Barbara Wakimoto, Conny Schütze, Nils Wiedemann, Anna Artati, Jerzy Adamski, Gerd Walz, Edmund R S Kunji, Craig Montell, Terry Watnick, Michael Köttgen
Published 2018-08-01