Interferon regulatory factor 2 binding protein 2: a new player of the innate immune response for stroke recovery

by Hsiao-Huei Chen, Alexandre F. R. Stewart
Published 2017-01-01

Activation of tyrosine phosphatases in the progression of Alzheimer's disease

by Alexandre F. R. Stewart, Hsiao-Huei Chen
Published 2020-01-01

Dabrafenib, an inhibitor of RIP3 kinase-dependent necroptosis, reduces ischemic brain injury

by Shelly A Cruz, Zhaohong Qin, Alexandre F. R. Stewart, Hsiao-Huei Chen
Published 2018-01-01

Ketamine's schizophrenia-like effects are prevented by targeting PTP1B

by Zhaohong Qin, Li Zhang, Michael A. Zasloff, Alexandre F.R. Stewart, Hsiao-Huei Chen
Published 2021-07-01

Neuronal protein-tyrosine phosphatase 1B hinders sensory-motor functional recovery and causes affective disorders in two different focal ischemic stroke models

by Shelly A Cruz, Zhaohong Qin, Konrad M Ricke, Alexandre F.R. Stewart, Hsiao-Huei Chen
Published 2021-01-01

Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors

by Li Zhang, Zhaohong Qin, Konrad M. Ricke, Shelly A. Cruz, Alexandre F. R. Stewart, Hsiao-Huei Chen
Published 2020-02-01

Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in a mouse model of Alzheimer's disease

by Li Zhang, Zhaohong Qin, Fariba Sharmin, Wei Lin, Konrad M. Ricke, Michael A. Zasloff, Alexandre F.R. Stewart, Hsiao-Huei Chen
Published 2021-08-01

Adiposity significantly modifies genetic risk for dyslipidemia[S]

by Christopher B. Cole, Majid Nikpay, Paulina Lau, Alexandre F.R. Stewart, Robert W. Davies, George A. Wells, Robert Dent, Ruth McPherson
Published 2014-11-01

Plasma PCSK9 levels are elevated with acute myocardial infarction in two independent retrospective angiographic studies.

by Naif A M Almontashiri, Ragnar O Vilmundarson, Nima Ghasemzadeh, Sonny Dandona, Robert Roberts, Arshed A Quyyumi, Hsiao-Huei Chen, Alexandre F R Stewart
Published 2014-01-01

Identification of a phosphorylation-dependent nuclear localization motif in interferon regulatory factor 2 binding protein 2.

by Allen C T Teng, Naif A M Al-Montashiri, Brian L M Cheng, Philip Lou, Pinar Ozmizrak, Hsiao-Huei Chen, Alexandre F R Stewart
Published 2011-01-01

Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury

by Shelly A. Cruz, Shelly A. Cruz, Shelly A. Cruz, Aswin Hari, Aswin Hari, Aswin Hari, Zhaohong Qin, Zhaohong Qin, Pascal Couture, Pascal Couture, Pascal Couture, Hua Huang, Hua Huang, Hua Huang, Diane C. Lagace, Diane C. Lagace, Diane C. Lagace, Alexandre F. R. Stewart, Alexandre F. R. Stewart, Hsiao-Huei Chen, Hsiao-Huei Chen, Hsiao-Huei Chen, Hsiao-Huei Chen, Hsiao-Huei Chen
Published 2017-07-01

Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease

by Jaana A. Hartiala, W. H. Wilson Tang, Zeneng Wang, Amanda L. Crow, Alexandre F. R. Stewart, Robert Roberts, Ruth McPherson, Jeanette Erdmann, Christina Willenborg, Stanley L. Hazen, Hooman Allayee
Published 2016-01-01

SPG7 Variant Escapes Phosphorylation-Regulated Processing by AFG3L2, Elevates Mitochondrial ROS, and Is Associated with Multiple Clinical Phenotypes

by Naif A.M. Almontashiri, Hsiao-Huei Chen, Ryan J. Mailloux, Takashi Tatsuta, Allen C.T. Teng, Ahmad B. Mahmoud, Tiffany Ho, Nicolas A.S. Stewart, Peter Rippstein, Mary Ellen Harper, Robert Roberts, Christina Willenborg, Jeanette Erdmann, Annalisa Pastore, Heidi M. McBride, Thomas Langer, Alexandre F.R. Stewart
Published 2014-05-01

Correction: Rare Copy Number Variants Contribute to Congenital Left-Sided Heart Disease

by Marc-Phillip Hitz, Louis-Philippe Lemieux-Perreault, Christian Marshall, Yassamin Feroz-Zada, Robbie Davies, Shi Wei Yang, Anath Christopher Lionel, Guylaine D'Amours, Emmanuelle Lemyre, Rebecca Cullum, Jean-Luc Bigras, Maryse Thibeault, Philippe Chetaille, Alexandre Montpetit, Paul Khairy, Bert Overduin, Sabine Klaassen, Pamela Hoodless, Philip Awadalla, Julie Hussin, Youssef Idaghdour, Mona Nemer, Alexandre F. R. Stewart, Cornelius Boerkoel, Stephen W. Scherer, Andrea Richter, Marie-Pierre Dubé, Gregor Andelfinger
Published 2013-03-01

Correction: Rare Copy Number Variants Contribute to Congenital Left-Sided Heart Disease.

by Marc-Phillip Hitz, Louis-Philippe Lemieux-Perreault, Christian Marshall, Yassamin Feroz-Zada, Robbie Davies, Shi Wei Yang, Anath Christopher Lionel, Guylaine D'Amours, Emmanuelle Lemyre, Rebecca Cullum, Jean-Luc Bigras, Maryse Thibeault, Philippe Chetaille, Alexandre Montpetit, Paul Khairy, Bert Overduin, Sabine Klaassen, Pamela Hoodless, Philip Awadalla, Julie Hussin, Youssef Idaghdour, Mona Nemer, Alexandre F. R. Stewart, Cornelius Boerkoel, Stephen W. Scherer, Andrea Richter, Marie-Pierre Dubé, Gregor Andelfinger
Published 2013-03-01

Rare copy number variants contribute to congenital left-sided heart disease.

by Marc-Phillip Hitz, Louis-Philippe Lemieux-Perreault, Christian Marshall, Yassamin Feroz-Zada, Robbie Davies, Shi Wei Yang, Anath Christopher Lionel, Guylaine D'Amours, Emmanuelle Lemyre, Rebecca Cullum, Jean-Luc Bigras, Maryse Thibeault, Philippe Chetaille, Alexandre Montpetit, Paul Khairy, Bert Overduin, Sabine Klaassen, Pamela Hoodless, Philip Awadalla, Julie Hussin, Youssef Idaghdour, Mona Nemer, Alexandre F R Stewart, Cornelius Boerkoel, Stephen W Scherer, Andrea Richter, Marie-Pierre Dubé, Gregor Andelfinger
Published 2012-09-01

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies.

by Christian Herder, Wouter Peeters, Thomas Illig, Jens Baumert, Dominique P V de Kleijn, Frans L Moll, Ulrike Poschen, Norman Klopp, Martina Müller-Nurasyid, Michael Roden, Michael Preuss, CARDIoGRAM Consortium, Mahir Karakas, Christa Meisinger, Barbara Thorand, Gerard Pasterkamp, Wolfgang Koenig, Themistocles L Assimes, Panos Deloukas, Jeanette Erdmann, Hilma Holm, Sekar Kathiresan, Inke R König, Ruth McPherson, Muredach P Reilly, Robert Roberts, Nilesh J Samani, Heribert Schunkert, Alexandre F R Stewart
Published 2011-01-01

Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias.

by Robert Clarke, Derrick A Bennett, Sarah Parish, Petra Verhoef, Mariska Dötsch-Klerk, Mark Lathrop, Peng Xu, Børge G Nordestgaard, Hilma Holm, Jemma C Hopewell, Danish Saleheen, Toshihiro Tanaka, Sonia S Anand, John C Chambers, Marcus E Kleber, Willem H Ouwehand, Yoshiji Yamada, Clara Elbers, Bas Peters, Alexandre F R Stewart, Muredach M Reilly, Barbara Thorand, Salim Yusuf, James C Engert, Themistocles L Assimes, Jaspal Kooner, John Danesh, Hugh Watkins, Nilesh J Samani, Rory Collins, Richard Peto, MTHFR Studies Collaborative Group
Published 2012-02-01

Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.

by Ville-Petteri Mäkinen, Mete Civelek, Qingying Meng, Bin Zhang, Jun Zhu, Candace Levian, Tianxiao Huan, Ayellet V Segrè, Sujoy Ghosh, Juan Vivar, Majid Nikpay, Alexandre F R Stewart, Christopher P Nelson, Christina Willenborg, Jeanette Erdmann, Stefan Blakenberg, Christopher J O'Donnell, Winfried März, Reijo Laaksonen, Stephen E Epstein, Sekar Kathiresan, Svati H Shah, Stanley L Hazen, Muredach P Reilly, Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Consortium, Aldons J Lusis, Nilesh J Samani, Heribert Schunkert, Thomas Quertermous, Ruth McPherson, Xia Yang, Themistocles L Assimes
Published 2014-07-01

Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease.

by Enrique Audain, Anna Wilsdon, Jeroen Breckpot, Jose M G Izarzugaza, Tomas W Fitzgerald, Anne-Karin Kahlert, Alejandro Sifrim, Florian Wünnemann, Yasset Perez-Riverol, Hashim Abdul-Khaliq, Mads Bak, Anne S Bassett, Woodrow D Benson, Felix Berger, Ingo Daehnert, Koenraad Devriendt, Sven Dittrich, Piers Ef Daubeney, Vidu Garg, Karl Hackmann, Kirstin Hoff, Philipp Hofmann, Gregor Dombrowsky, Thomas Pickardt, Ulrike Bauer, Bernard D Keavney, Sabine Klaassen, Hans-Heiner Kramer, Christian R Marshall, Dianna M Milewicz, Scott Lemaire, Joseph S Coselli, Michael E Mitchell, Aoy Tomita-Mitchell, Siddharth K Prakash, Karl Stamm, Alexandre F R Stewart, Candice K Silversides, Reiner Siebert, Brigitte Stiller, Jill A Rosenfeld, Inga Vater, Alex V Postma, Almuth Caliebe, J David Brook, Gregor Andelfinger, Matthew E Hurles, Bernard Thienpont, Lars Allan Larsen, Marc-Phillip Hitz
Published 2021-07-01