Multi-state design of flexible proteins predicts sequences optimal for conformational change.

by Marion F Sauer, Alexander M Sevy, James E Crowe, Jens Meiler
Published 2020-02-01

Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences.

by Alexander M Sevy, Tim M Jacobs, James E Crowe, Jens Meiler
Published 2015-07-01

Integrating linear optimization with structural modeling to increase HIV neutralization breadth.

by Alexander M Sevy, Swetasudha Panda, James E Crowe, Jens Meiler, Yevgeniy Vorobeychik
Published 2018-02-01

Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures

by Alexander M. Sevy, Cinque Soto, Robin G. Bombardi, Jens Meiler, James E. Crowe
Published 2019-12-01