West Nile Virus Spreads Transsynaptically within the Pathways of Motor Control: Anatomical and Ultrastructural Mapping of Neuronal Virus Infection in the Primate Central Nervous Sy...

by Olga A Maximova, John G Bernbaum, Alexander G Pletnev
Published 2016-09-01

Synergistic Internal Ribosome Entry Site/MicroRNA-Based Approach for Flavivirus Attenuation and Live Vaccine Development

by Konstantin A. Tsetsarkin, Guangping Liu, Evgeniya Volkova, Alexander G. Pletnev, Rino Rappuoli
Published 2017-04-01

Novel Approach for Insertion of Heterologous Sequences into Full-Length ZIKV Genome Results in Superior Level of Gene Expression and Insert Stability

by Evgeniya Volkova, Konstantin A. Tsetsarkin, Emilia Sippert, Felipe Assis, Guangping Liu, Maria Rios, Alexander G. Pletnev
Published 2020-01-01

Stable and Highly Immunogenic MicroRNA-Targeted Single-Dose Live Attenuated Vaccine Candidate against Tick-Borne Encephalitis Constructed Using Genetic Backbone of Langat Virus

by Konstantin A. Tsetsarkin, Olga A. Maximova, Guangping Liu, Heather Kenney, Natalya L. Teterina, Alexander G. Pletnev
Published 2019-04-01

The Roles of prM-E Proteins in Historical and Epidemic Zika Virus-mediated Infection and Neurocytotoxicity

by Ge Li, Sandra Bos, Konstantin A. Tsetsarkin, Alexander G. Pletnev, Philippe Desprès, Gilles Gadea, Richard Y. Zhao
Published 2019-02-01

Dual miRNA targeting restricts host range and attenuates neurovirulence of flaviviruses.

by Konstantin A Tsetsarkin, Guangping Liu, Heather Kenney, Jose Bustos-Arriaga, Christopher T Hanson, Stephen S Whitehead, Alexander G Pletnev
Published 2015-04-01

Zika virus tropism during early infection of the testicular interstitium and its role in viral pathogenesis in the testes.

by Konstantin A Tsetsarkin, Joshua A Acklin, Guangping Liu, Heather Kenney, Natalia L Teterina, Alexander G Pletnev, Jean K Lim
Published 2020-07-01

A Full-Length Infectious cDNA Clone of Zika Virus from the 2015 Epidemic in Brazil as a Genetic Platform for Studies of Virus-Host Interactions and Vaccine Development

by Konstantin A. Tsetsarkin, Heather Kenney, Rubing Chen, Guangping Liu, Hasmik Manukyan, Stephen S. Whitehead, Majid Laassri, Konstantin Chumakov, Alexander G. Pletnev
Published 2016-08-01

Epididymal epithelium propels early sexual transmission of Zika virus in the absence of interferon signaling

by Alexander G. Pletnev, Olga A. Maximova, Guangping Liu, Heather Kenney, Bianca M. Nagata, Tatiana Zagorodnyaya, Ian Moore, Konstantin Chumakov, Konstantin A. Tsetsarkin
Published 2021-04-01

Virus infection of the CNS disrupts the immune-neural-synaptic axis via induction of pleiotropic gene regulation of host responses

by Olga A Maximova, Daniel E Sturdevant, John C Kash, Kishore Kanakabandi, Yongli Xiao, Mahnaz Minai, Ian N Moore, Jeff Taubenberger, Craig Martens, Jeffrey I Cohen, Alexander G Pletnev
Published 2021-02-01

Flavivirus Infection of Ixodes scapularis (Black-Legged Tick) Ex Vivo Organotypic Cultures and Applications for Disease Control

by Jeffrey M. Grabowski, Konstantin A. Tsetsarkin, Dan Long, Dana P. Scott, Rebecca Rosenke, Tom G. Schwan, Luwanika Mlera, Danielle K. Offerdahl, Alexander G. Pletnev, Marshall E. Bloom, Vincent R. Racaniello
Published 2017-08-01

Routes of Zika virus dissemination in the testis and epididymis of immunodeficient mice

by Konstantin A. Tsetsarkin, Olga A. Maximova, Guangping Liu, Heather Kenney, Natalia Teterina, Marshall E. Bloom, Jeffrey M. Grabowski, Luwanika Mlera, Bianca M. Nagata, Ian Moore, Craig Martens, Emerito Amaro-Carambot, Elaine W. Lamirande, Stephen S. Whitehead, Alexander G. Pletnev
Published 2018-12-01