Pleiotropic Cellular Functions of PARP1 in Longevity and Aging: Genome Maintenance Meets Inflammation

by Aswin Mangerich, Alexander Bürkle
Published 2012-01-01

Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy

by Annika Krüger, Alexander Bürkle, Karin Hauser, Aswin Mangerich
Published 2020-05-01

Chromatin composition is changed by poly(ADP-ribosyl)ation during chromatin immunoprecipitation.

by Sascha Beneke, Kirstin Meyer, Anja Holtz, Katharina Hüttner, Alexander Bürkle
Published 2012-01-01

Procaine–The Controversial Geroprotector Candidate: New Insights Regarding Its Molecular and Cellular Effects

by Daniela Gradinaru, Anca Ungurianu, Denisa Margina, Maria Moreno-Villanueva, Alexander Bürkle
Published 2021-01-01

DNA damage in Nijmegen Breakage Syndrome cells leads to PARP hyperactivation and increased oxidative stress.

by Harald Krenzlin, Ilja Demuth, Bastian Salewsky, Petra Wessendorf, Kathrin Weidele, Alexander Bürkle, Martin Digweed
Published 2012-01-01

Influence of Acute Exercise on DNA Repair and PARP Activity before and after Irradiation in Lymphocytes from Trained and Untrained Individuals

by Maria Moreno-Villanueva, Andreas Kramer, Tabea Hammes, Maria Venegas-Carro, Patrick Thumm, Alexander Bürkle, Markus Gruber
Published 2019-06-01

Cardiorespiratory and Neuromuscular Demand of Daily Centrifugation: Results From the 60-Day AGBRESA Bed Rest Study

by Andreas Kramer, María Venegas-Carro, Edwin Mulder, Jessica K. Lee, María Moreno-Villanueva, Alexander Bürkle, Markus Gruber
Published 2020-09-01

Prion protein in milk.

by Nicola Franscini, Ahmed El Gedaily, Ulrich Matthey, Susanne Franitza, Man-Sun Sy, Alexander Bürkle, Martin Groschup, Ueli Braun, Ralph Zahn
Published 2006-01-01

Synergistic Effects of Weightlessness, Isoproterenol, and Radiation on DNA Damage Response and Cytokine Production in Immune Cells

by Maria Moreno-Villanueva, Alan H. Feiveson, Stephanie Krieger, AnneMarie Kay Brinda, Gudrun von Scheven, Alexander Bürkle, Brian Crucian, Honglu Wu
Published 2018-11-01

The Radioprotective Effect of Procaine and Procaine-Derived Product Gerovital H3 in Lymphocytes from Young and Aged Individuals

by Anca Ungurianu, Denisa Margina, Claudia Borsa, Cristina Ionescu, Gudrun von Scheven, Lucie Oziol, Philippe Faure, Yves Artur, Alexander Bürkle, Daniela Gradinaru, Maria Moreno-Villanueva
Published 2020-01-01

The oncoprotein DEK affects the outcome of PARP1/2 inhibition during mild replication stress.

by Magdalena Ganz, Christopher Vogel, Christina Czada, Vera Jörke, Eva Christina Gwosch, Rebecca Kleiner, Agnieszka Pierzynska-Mach, Francesca Cella Zanacchi, Alberto Diaspro, Ferdinand Kappes, Alexander Bürkle, Elisa Ferrando-May
Published 2019-01-01

The role of nibrin in doxorubicin-induced apoptosis and cell senescence in Nijmegen Breakage Syndrome patients lymphocytes.

by Olga Alster, Anna Bielak-Zmijewska, Grazyna Mosieniak, Maria Moreno-Villanueva, Wioleta Dudka-Ruszkowska, Aleksandra Wojtala, Monika Kusio-Kobiałka, Zbigniew Korwek, Alexander Burkle, Katarzyna Piwocka, Jan K Siwicki, Ewa Sikora
Published 2014-01-01

Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK-AGE Project

by Daniela Weber, Wolfgang Stuetz, Olivier Toussaint, Florence Debacq-Chainiaux, Martijn E. T. Dollé, Eugène Jansen, Efstathios S. Gonos, Claudio Franceschi, Ewa Sikora, Antti Hervonen, Nicolle Breusing, Thilo Sindlinger, María Moreno-Villanueva, Alexander Bürkle, Tilman Grune
Published 2017-01-01

Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35–74 Years) General Population: A Cross-Sectional Study in Six European Countries

by Wolfgang Stuetz, Daniela Weber, Martijn E. T. Dollé, Eugène Jansen, Beatrix Grubeck-Loebenstein, Simone Fiegl, Olivier Toussaint, Juergen Bernhardt, Efstathios S. Gonos, Claudio Franceschi, Ewa Sikora, María Moreno-Villanueva, Nicolle Breusing, Tilman Grune, Alexander Bürkle
Published 2016-09-01

Medication Intake Is Associated with Lower Plasma Carotenoids and Higher Fat-Soluble Vitamins in the Cross-Sectional MARK-AGE Study in Older Individuals

by Daniela Weber, Bastian Kochlik, Wolfgang Stuetz, Martijn E. T. Dollé, Eugène H. J. M. Jansen, Beatrix Grubeck-Loebenstein, Florence Debacq-Chainiaux, Jürgen Bernhardt, Efstathios S. Gonos, Miriam Capri, Claudio Franceschi, Ewa Sikora, María Moreno-Villanueva, Alexander Bürkle, Tilman Grune
Published 2020-07-01

Gender- and age-dependencies of oxidative stress, as detected based on the steady state concentrations of different biomarkers in the MARK-AGE study

by Ilya Pinchuk, Daniela Weber, Bastian Kochlik, Wolfgang Stuetz, Olivier Toussaint, Florence Debacq-Chainiaux, Martijn E.T. Dollé, Eugène H.J.M. Jansen, Efstathios S. Gonos, Ewa Sikora, Nicolle Breusing, Daniela Gradinaru, Thilo Sindlinger, María Moreno-Villanueva, Alexander Bürkle, Tilman Grune, Dov Lichtenberg
Published 2019-06-01

The 'COmorBidity in Relation to AIDS' (COBRA) cohort: Design, methods and participant characteristics.

by Davide De Francesco, Ferdinand W Wit, James H Cole, Neeltje A Kootstra, Alan Winston, Caroline A Sabin, Jonathan Underwood, Rosan A van Zoest, Judith Schouten, Katherine W Kooij, Maria Prins, Giovanni Guaraldi, Matthan W A Caan, David Burger, Claudio Franceschi, Claude Libert, Alexander Bürkle, Peter Reiss, COmorBidity in Relation to AIDS (COBRA) collaboration
Published 2018-01-01

Microbiome in Blood Samples From the General Population Recruited in the MARK-AGE Project: A Pilot Study

by Patrizia D’Aquila, Robertina Giacconi, Marco Malavolta, Francesco Piacenza, Alexander Bürkle, María Moreno Villanueva, María Moreno Villanueva, Martijn E. T. Dollé, Eugène Jansen, Tilman Grune, Tilman Grune, Efstathios S. Gonos, Claudio Franceschi, Claudio Franceschi, Miriam Capri, Miriam Capri, Beatrix Grubeck-Loebenstein, Ewa Sikora, Olivier Toussaint, Florence Debacq-Chainiaux, Antti Hervonen, Mikko Hurme, P. Eline Slagboom, Christiane Schön, Jürgen Bernhardt, Nicolle Breusing, Giuseppe Passarino, Mauro Provinciali, Dina Bellizzi
Published 2021-07-01