Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms

by Alessio Nocentini, Alessandro Bonardi, Paola Gratteri, Bruno Cerra, Antimo Gioiello, Claudiu T. Supuran
Published 2018-01-01

The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors

by Aleksandrs Pustenko, Alessio Nocentini, Paola Gratteri, Alessandro Bonardi, Igor Vozny, Raivis Žalubovskis, Claudiu T. Supuran
Published 2020-01-01

Novel insights on saccharin- and acesulfame-based carbonic anhydrase inhibitors: design, synthesis, modelling investigations and biological activity evaluation

by Paolo Guglielmi, Giulia Rotondi, Daniela Secci, Andrea Angeli, Paola Chimenti, Alessio Nocentini, Alessandro Bonardi, Paola Gratteri, Simone Carradori, Claudiu T. Supuran
Published 2020-01-01

Inhibition of α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae with aromatic sulphonamides and clinically licenced drugs – a joint docking/molecular d...

by Alessandro Bonardi, Alessio Nocentini, Sameh Mohamed Osman, Fatmah Ali Alasmary, Tahani Mazyad Almutairi, Dalal Saied Abdullah, Paola Gratteri, Claudiu T. Supuran
Published 2021-01-01

Novel Diamide-Based Benzenesulfonamides as Selective Carbonic Anhydrase IX Inhibitors Endowed with Antitumor Activity: Synthesis, Biological Evaluation and In Silico Insights

by Mohamed A. Abdelrahman, Wagdy M. Eldehna, Alessio Nocentini, Silvia Bua, Sara T. Al-Rashood, Ghada S. Hassan, Alessandro Bonardi, Abdulrahman A. Almehizia, Hamad M. Alkahtani, Amal Alharbi, Paola Gratteri, Claudiu T. Supuran
Published 2019-05-01