Evidence that C/EBP-β LAP Increases Fat Metabolism and Protects Against Diet-Induced Obesity in Response to mTOR Inhibition

by Alessandro Bitto, Nicole Tatom, Thomas Krivak, Peter Grotz, Matt Kaeberlein
Published 2021-09-01

Astrocyte senescence as a component of Alzheimer's disease.

by Rekha Bhat, Elizabeth P Crowe, Alessandro Bitto, Michelle Moh, Christos D Katsetos, Fernando U Garcia, Frederick Bradley Johnson, John Q Trojanowski, Christian Sell, Claudio Torres
Published 2012-01-01

Long-term IGF-I exposure decreases autophagy and cell viability.

by Alessandro Bitto, Chad Lerner, Claudio Torres, Michaela Roell, Marco Malaguti, Viviana Perez, Antonello Lorenzini, Silvana Hrelia, Yuji Ikeno, Michelle Elizabeth Matzko, Roger McCarter, Christian Sell
Published 2010-09-01

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice

by Alessandro Bitto, Takashi K Ito, Victor V Pineda, Nicolas J LeTexier, Heather Z Huang, Elissa Sutlief, Herman Tung, Nicholas Vizzini, Belle Chen, Kaleb Smith, Daniel Meza, Masanao Yajima, Richard P Beyer, Kathleen F Kerr, Daniel J Davis, Catherine H Gillespie, Jessica M Snyder, Piper M Treuting, Matt Kaeberlein
Published 2016-08-01

Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans.

by Christopher F Bennett, Jane J Kwon, Christine Chen, Joshua Russell, Kathlyn Acosta, Nikolay Burnaevskiy, Matthew M Crane, Alessandro Bitto, Helen Vander Wende, Marissa Simko, Victor Pineda, Ryan Rossner, Brian M Wasko, Haeri Choi, Shiwen Chen, Shirley Park, Gholamali Jafari, Bryan Sands, Carissa Perez Olsen, Alexander R Mendenhall, Philip G Morgan, Matt Kaeberlein
Published 2017-03-01

Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency

by Takashi K. Ito, Takashi K. Ito, Takashi K. Ito, Chenhao Lu, Jacob Khan, Quy Nguyen, Heather Z. Huang, Dayae Kim, James Phillips, Jo Tan, Yenna Lee, Tuyet Nguyen, Samy Khessib, Natalie Lim, Surapat Mekvanich, Joshua Oh, Victor V. Pineda, Weirong Wang, Weirong Wang, Weirong Wang, Alessandro Bitto, Jonathan Y. An, John F. Morton, Mitsutoshi Setou, Mitsutoshi Setou, Warren C. Ladiges, Matt Kaeberlein
Published 2017-09-01

Corrigendum: Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency

by Takashi K. Ito, Takashi K. Ito, Takashi K. Ito, Chenhao Lu, Jacob Khan, Quy Nguyen, Heather Z. Huang, Dayae Kim, James J. Phillips, Jo Tan, Yenna Lee, Tuyet Nguyen, Samy Khessib, Natalie Lim, Surapat Mekvanich, Joshua Oh, Victor V. Pineda, Weirong Wang, Weirong Wang, Weirong Wang, Alessandro Bitto, Jonathan Y. An, John F. Morton, Mitsutoshi Setou, Mitsutoshi Setou, Warren C. Ladiges, Matt Kaeberlein
Published 2017-12-01