A genetically encoded FRET lactate sensor and its use to detect the Warburg effect in single cancer cells.

by Alejandro San Martín, Sebastián Ceballo, Iván Ruminot, Rodrigo Lerchundi, Wolf B Frommer, Luis Felipe Barros
Published 2013-01-01

MitoToxy assay: A novel cell-based method for the assessment of metabolic toxicity in a multiwell plate format using a lactate FRET nanosensor, Laconic.

by Yasna Contreras-Baeza, Sebastián Ceballo, Robinson Arce-Molina, Pamela Y Sandoval, Karin Alegría, Luis Felipe Barros, Alejandro San Martín
Published 2019-01-01

Imaging mitochondrial flux in single cells with a FRET sensor for pyruvate.

by Alejandro San Martín, Sebastián Ceballo, Felipe Baeza-Lehnert, Rodrigo Lerchundi, Rocío Valdebenito, Yasna Contreras-Baeza, Karin Alegría, L Felipe Barros
Published 2014-01-01

A highly responsive pyruvate sensor reveals pathway-regulatory role of the mitochondrial pyruvate carrier MPC

by Robinson Arce-Molina, Francisca Cortés-Molina, Pamela Y Sandoval, Alex Galaz, Karin Alegría, Stefanie Schirmeier, L Felipe Barros, Alejandro San Martín
Published 2020-03-01