Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladder.

by Boris Y Shorning, David Griffiths, Alan R Clarke
Published 2011-01-01

APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression

by Noha-Ehssan Mohamed, Trevor Hay, Karen R. Reed, Matthew J. Smalley, Alan R. Clarke
Published 2019-07-01

High Dose Atorvastatin Associated with Increased Risk of Significant Hepatotoxicity in Comparison to Simvastatin in UK GPRD Cohort.

by Alan T Clarke, Paul C D Johnson, Gillian C Hall, Ian Ford, Peter R Mills
Published 2016-01-01

Brg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestine.

by Aliaksei Z Holik, Madeleine Young, Joanna Krzystyniak, Geraint T Williams, Daniel Metzger, Boris Y Shorning, Alan R Clarke
Published 2014-07-01

Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine.

by Boris Y Shorning, Joanna Zabkiewicz, Afshan McCarthy, Helen B Pearson, Douglas J Winton, Owen J Sansom, Alan Ashworth, Alan R Clarke
Published 2009-01-01

Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine

by Boris Y. Shorning, Joanna Zabkiewicz, Afshan McCarthy, Helen B. Pearson, Douglas J. Winton, Owen J. Sansom, Alan Ashworth, Alan R. Clarke
Published 2009-01-01

Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine.

by Boris Y. Shorning, Joanna Zabkiewicz, Afshan McCarthy, Helen B. Pearson, Douglas J. Winton, Owen J. Sansom, Alan Ashworth, Alan R. Clarke
Published 2009-01-01

Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine.

by Boris Y Shorning, Joanna Zabkiewicz, Afshan McCarthy, Helen B Pearson, Douglas J Winton, Owen J Sansom, Alan Ashworth, Alan R Clarke
Published 2019-01-01

Cited1 deficiency suppresses intestinal tumorigenesis.

by Valérie Méniel, Fei Song, Toby Phesse, Madeleine Young, Oliver Poetz, Lee Parry, John R Jenkins, Geraint T Williams, Sally L Dunwoodie, Alastair Watson, Alan R Clarke
Published 2013-01-01

NAP1L1: A Novel Human Colorectal Cancer Biomarker Derived From Animal Models of Apc Inactivation

by Cleberson J. S. Queiroz, Cleberson J. S. Queiroz, Fei Song, Fei Song, Karen R. Reed, Karen R. Reed, Nadeem Al-Khafaji, Alan R. Clarke, Dale Vimalachandran, Fabio Miyajima, Fabio Miyajima, D. Mark Pritchard, John R. Jenkins
Published 2020-08-01

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo.

by Michael Buchert, Dimitris Athineos, Helen E Abud, Zoe D Burke, Maree C Faux, Michael S Samuel, Andrew G Jarnicki, Catherine E Winbanks, Ian P Newton, Valerie S Meniel, Hiromu Suzuki, Steven A Stacker, Inke S Näthke, David Tosh, Joerg Huelsken, Alan R Clarke, Joan K Heath, Owen J Sansom, Matthias Ernst
Published 2010-01-01

3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.

by Luned M Badder, Andrew J Hollins, Bram Herpers, Kuan Yan, Kenneth B Ewan, Mairian Thomas, Jennifer R Shone, Delyth A Badder, Marc Naven, Kevin E Ashelford, Rachel Hargest, Alan R Clarke, Christina Esdar, Hans-Peter Buchstaller, J Mark Treherne, Sylvia Boj, Bahar Ramezanpour, Dirk Wienke, Leo S Price, Paul H Shaw, Trevor C Dale
Published 2020-01-01