Diethylcarbamazine increases activation of voltage-activated potassium (SLO-1) currents in Ascaris suum and potentiates effects of emodepside.

by Samuel K Buxton, Alan P Robertson, Richard J Martin
Published 2014-01-01

Curiouser and Curiouser: The Macrocyclic Lactone, Abamectin, Is also a Potent Inhibitor of Pyrantel/Tribendimidine Nicotinic Acetylcholine Receptors of Gastro-Intestinal Worms.

by Melanie Abongwa, Samuel K Buxton, Alan P Robertson, Richard J Martin
Published 2016-01-01

Tribendimidine: mode of action and nAChR subtype selectivity in Ascaris and Oesophagostomum.

by Alan P Robertson, Sreekanth Puttachary, Samuel K Buxton, Richard J Martin
Published 2015-02-01

Proteomic analysis of adult Ascaris suum fluid compartments and secretory products.

by James F Chehayeb, Alan P Robertson, Richard J Martin, Timothy G Geary
Published 2014-06-01

The Ascaris suum nicotinic receptor, ACR-16, as a drug target: Four novel negative allosteric modulators from virtual screening

by Fudan Zheng, Alan P. Robertson, Melanie Abongwa, Edward W. Yu, Richard J. Martin
Published 2016-04-01

Functional characterization of a novel family of acetylcholine-gated chloride channels in Schistosoma mansoni.

by Kevin MacDonald, Samuel Buxton, Michael J Kimber, Tim A Day, Alan P Robertson, Paula Ribeiro
Published 2014-06-01

Emodepside has sex-dependent immobilizing effects on adult Brugia malayi due to a differentially spliced binding pocket in the RCK1 region of the SLO-1 K channel.

by Sudhanva S Kashyap, Saurabh Verma, Denis Voronin, Sara Lustigman, Daniel Kulke, Alan P Robertson, Richard J Martin
Published 2019-09-01

Cholinergic receptors on intestine cells of Ascaris suum and activation of nAChRs by levamisole

by Mark McHugh, Paul Williams, Saurabh Verma, Jo Anne Powell-Coffman, Alan P. Robertson, Richard J. Martin
Published 2020-08-01

Anthelmintic resistance and homeostatic plasticity (Brugia malayi)

by Sudhanva S. Kashyap, Saurabh Verma, Mark McHugh, Mengisteab Wolday, Paul D. Williams, Alan P. Robertson, Richard J. Martin
Published 2021-07-01

Monepantel is a non-competitive antagonist of nicotinic acetylcholine receptors from Ascaris suum and Oesophagostomum dentatum

by Melanie Abongwa, Djordje S. Marjanovic, James G. Tipton, Fudan Zheng, Richard J. Martin, Sasa M. Trailovic, Alan P. Robertson
Published 2018-04-01

(S)-5-ethynyl-anabasine, a novel compound, is a more potent agonist than other nicotine alkaloids on the nematode Asu-ACR-16 receptor

by Fudan Zheng, Xiangwei Du, Tsung-Han Chou, Alan P. Robertson, Edward W. Yu, Brett VanVeller, Richard J. Martin
Published 2017-04-01

FMRFamide-like peptides (FLPs) enhance voltage-gated calcium currents to elicit muscle contraction in the human parasite Schistosoma mansoni.

by Ekaterina Novozhilova, Michael J Kimber, Hai Qian, Paul McVeigh, Alan P Robertson, Mostafa Zamanian, Aaron G Maule, Tim A Day
Published 2010-08-01

The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits.

by Sally M Williamson, Alan P Robertson, Laurence Brown, Tracey Williams, Debra J Woods, Richard J Martin, David B Sattelle, Adrian J Wolstenholme
Published 2009-07-01

Menthol acts as a positive allosteric modulator on nematode levamisole sensitive nicotinic acetylcholine receptors

by Shivani Choudhary, Djordje S. Marjianović, Colin R. Wong, Xiaoyu Zhang, Melanie Abongwa, Joel R. Coats, Saša M. Trailović, Richard J. Martin, Alan P. Robertson
Published 2019-04-01

Investigation of acetylcholine receptor diversity in a nematode parasite leads to characterization of tribendimidine- and derquantel-sensitive nAChRs.

by Samuel K Buxton, Claude L Charvet, Cedric Neveu, Jacques Cabaret, Jacques Cortet, Nicolas Peineau, Melanie Abongwa, Elise Courtot, Alan P Robertson, Richard J Martin
Published 2014-01-01

EAT-18 is an essential auxiliary protein interacting with the non-alpha nAChR subunit EAT-2 to form a functional receptor.

by Shivani Choudhary, Samuel K Buxton, Sreekanth Puttachary, Saurabh Verma, Gunnar R Mair, Ciaran J McCoy, Barbara J Reaves, Adrian J Wolstenholme, Richard J Martin, Alan P Robertson
Published 2020-04-01

Filaricidal activity of Daniellia oliveri and Psorospermum febrifugum extracts

by Melanie Abongwa, Moses Samje, Godfred A. Ayimele, Smith B. Babiaka, Christina Bulman, Judy Sakanari, Nick J. Koszewski, Saurabh Verma, Jesse Goff, Fidelis Cho-Ngwa, Richard J. Martin, Alan P. Robertson
Published 2021-06-01

Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions

by Andrew C. Kotze, Peter W. Hunt, Philip Skuce, Georg von Samson-Himmelstjerna, Richard J. Martin, Heinz Sager, Jürgen Krücken, Jane Hodgkinson, Anne Lespine, Aaron R. Jex, John S. Gilleard, Robin N. Beech, Adrian J. Wolstenholme, Janina Demeler, Alan P. Robertson, Claude L. Charvet, Cedric Neveu, Ronald Kaminsky, Lucien Rufener, Melanie Alberich, Cecile Menez, Roger K. Prichard
Published 2014-12-01