The frequency of neoantigens per somatic mutation rather than overall mutational load or number of predicted neoantigens per se is a prognostic factor in ovarian clear cell carcino...

by Hirokazu Matsushita, Kosei Hasegawa, Katsutoshi Oda, Shogo Yamamoto, Akira Nishijima, Yuichi Imai, Kayo Asada, Yuji Ikeda, Takahiro Karasaki, Keiichi Fujiwara, Hiroyuki Aburatani, Kazuhiro Kakimi
Published 2017-08-01

Neoantigen load and HLA-class I expression identify a subgroup of tumors with a T-cell-inflamed phenotype and favorable prognosis in homologous recombination-proficient high-grade...

by Yukari Kobayashi, Kazuhiro Kakimi, Hirokazu Matsushita, Katsutoshi Oda, Shogo Yamamoto, Kayo Asada, Takahiro Karasaki, Akira Nishijima, Takahide Nejo, Yuji Ikeda, Manami Miyai, Yusuke Takahashi, Rui Yamaguchi, Hiroyuki Aburatani
Published 2020-06-01

The oncogene KRAS promotes cancer cell dissemination by stabilizing spheroid formation via the MEK pathway

by Juri Ogishima, Ayumi Taguchi, Akira Kawata, Kei Kawana, Mitsuyo Yoshida, Yuki Yoshimatsu, Masakazu Sato, Hiroe Nakamura, Yoshiko Kawata, Akira Nishijima, Asaha Fujimoto, Kensuke Tomio, Katsuyuki Adachi, Takeshi Nagamatsu, Katsutoshi Oda, Tohru Kiyono, Yutaka Osuga, Tomoyuki Fujii
Published 2018-12-01