Comparisons between dipeptidyl peptidase-4 inhibitors and other classes of hypoglycemic drugs using two distinct biomarkers of pancreatic beta-cell function: A meta-analysis.

by Masahiro Takahashi, Misa Shibasaki, Hirotoshi Echizen, Akifumi Kushiyama
Published 2020-01-01

Retinal blood flow dysregulation precedes neural retinal dysfunction in type 2 diabetic mice

by Junya Hanaguri, Harumasa Yokota, Masahisa Watanabe, Satoru Yamagami, Akifumi Kushiyama, Lih Kuo, Taiji Nagaoka
Published 2021-09-01

Characteristics Associated with Early Worsening of Retinopathy in Patients with Type 2 Diabetes Diagnosed with Retinopathy at Their First Visit: A Retrospective Observational Study

by Sayaka Wakabayashi Sugawa, Yoko Yoshida, Yusuke Hikima, Haruhiko Sato, Akira Shimada, Mitsuhiko Noda, Akifumi Kushiyama
Published 2021-01-01

Association of gait speed and grip strength with risk of cardiovascular events in patients on haemodialysis: a prospective study

by Atsumi Kuki, Kentaro Tanaka, Akifumi Kushiyama, Yoshihide Tanaka, Shuta Motonishi, Yasuji Sugano, Toru Furuya, Takashi Ozawa
Published 2019-05-01

Quantitative sonographic assessment of quadriceps muscle thickness for fall injury prediction in patients undergoing maintenance hemodialysis: an observational cohort study

by Asuka Sai, Kentaro Tanaka, Yasushi Ohashi, Akifumi Kushiyama, Yoshihide Tanaka, Shuta Motonishi, Ken Sakai, Shigeko Hara, Takashi Ozawa
Published 2021-05-01

Serum uric acid is an independent predictor of new-onset diabetes after living-donor kidney transplantation

by Kentaro Tanaka, Ken Sakai, Akifumi Kushiyama, Shigeko Hara, Masakazu Hattori, Yasushi Ohashi, Masaki Muramatsu, Takeshi Kawamura, Seiichiro Shishido, Atsushi Aikawa
Published 2018-07-01

Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages

by Hiroki Yamazaki, Akifumi Kushiyama, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Yusuke Nakatsu, Takako Kikuchi, Sunao Kaneko, Hirotoshi Tanaka, Tomoichiro Asano
Published 2018-01-01

Roles of Gut-Derived Secretory Factors in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Their Possible Clinical Applications

by Hirofumi Okubo, Akifumi Kushiyama, Yusuke Nakatsu, Takeshi Yamamotoya, Yasuka Matsunaga, Midori Fujishiro, Hideyuki Sakoda, Haruya Ohno, Masayasu Yoneda, Tomoichiro Asano
Published 2018-10-01

Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations

by Yusuke Nakatsu, Yasuka Matsunaga, Takeshi Yamamotoya, Koji Ueda, Yuki Inoue, Keiichi Mori, Hideyuki Sakoda, Midori Fujishiro, Hiraku Ono, Akifumi Kushiyama, Tomoichiro Asano
Published 2016-09-01

C-Peptide Level in Fasting Plasma and Pooled Urine Predicts HbA1c after Hospitalization in Patients with Type 2 Diabetes Mellitus.

by Remi Sonoda, Kentaro Tanaka, Takako Kikuchi, Yukiko Onishi, Toshiko Takao, Tazu Tahara, Yoko Yoshida, Naoki Suzawa, Shoji Kawazu, Yasuhiko Iwamoto, Akifumi Kushiyama
Published 2016-01-01

Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis

by Akifumi Kushiyama, Yusuke Nakatsu, Yasuka Matsunaga, Takeshi Yamamotoya, Keiichi Mori, Koji Ueda, Yuki Inoue, Hideyuki Sakoda, Midori Fujishiro, Hiraku Ono, Tomoichiro Asano
Published 2016-01-01

Carnosic Acid and Carnosol Activate AMPK, Suppress Expressions of Gluconeogenic and Lipogenic Genes, and Inhibit Proliferation of HepG2 Cells

by Shun Hasei, Takeshi Yamamotoya, Yusuke Nakatsu, Yukino Ohata, Shota Itoga, Yuji Nonaka, Yasuka Matsunaga, Hideyuki Sakoda, Midori Fujishiro, Akifumi Kushiyama, Tomoichiro Asano
Published 2021-04-01

Reduced SHARPIN and LUBAC Formation May Contribute to CCl4- or Acetaminophen-Induced Liver Cirrhosis in Mice

by Takeshi Yamamotoya, Yusuke Nakatsu, Yasuka Matsunaga, Toshiaki Fukushima, Hiroki Yamazaki, Sunao Kaneko, Midori Fujishiro, Takako Kikuchi, Akifumi Kushiyama, Fuminori Tokunaga, Tomoichiro Asano, Hideyuki Sakoda
Published 2017-02-01

Effect of postprandial hyperglycemia at clinic visits on the incidence of retinopathy in patients with type 2 diabetes: An analysis using real‐world long‐term follow‐up data

by Toshiko Takao, Kazuyuki Takahashi, Yoko Yoshida, Akifumi Kushiyama, Yukiko Onishi, Tazu Tahara, Asuka Shimmei, Takako Kikuchi, Machi Suka, Hiroyuki Yanagisawa, Yasuhiko Iwamoto, Masato Kasuga
Published 2020-07-01

Impact of Plasma Xanthine Oxidoreductase Activity on the Mechanisms of Distal Symmetric Polyneuropathy Development in Patients with Type 2 Diabetes

by Midori Fujishiro, Hisamitsu Ishihara, Katsuhiko Ogawa, Takayo Murase, Takashi Nakamura, Kentaro Watanabe, Hideyuki Sakoda, Hiraku Ono, Takeshi Yamamotoya, Yusuke Nakatsu, Tomoichiro Asano, Akifumi Kushiyama
Published 2021-08-01

Pathological Role of Pin1 in the Development of DSS-Induced Colitis

by Yasuka Matsunaga, Shun Hasei, Takeshi Yamamotoya, Hiroaki Honda, Akifumi Kushiyama, Hideyuki Sakoda, Midori Fujishiro, Hiraku Ono, Hisanaka Ito, Takayoshi Okabe, Tomoichiro Asano, Yusuke Nakatsu
Published 2021-05-01

Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines.

by Ryuhei Kanaoka, Akifumi Kushiyama, Yasuyuki Seno, Yusuke Nakatsu, Yasuka Matsunaga, Toshiaki Fukushima, Yoshihiro Tsuchiya, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Hideaki Kamata, Akio Matsubara, Tomoichiro Asano
Published 2015-01-01

The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic A...

by Yusuke Nakatsu, Hiroki Kokubo, Batmunkh Bumdelger, Masao Yoshizumi, Takeshi Yamamotoya, Yasuka Matsunaga, Koji Ueda, Yuki Inoue, Masa-Ki Inoue, Midori Fujishiro, Akifumi Kushiyama, Hiraku Ono, Hideyuki Sakoda, Tomoichiro Asano
Published 2017-08-01

The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model

by Masa-Ki Inoue, Takeshi Yamamotoya, Yusuke Nakatsu, Koji Ueda, Yuki Inoue, Yasuka Matsunaga, Hideyuki Sakoda, Midori Fujishiro, Hiraku Ono, Kenichi Morii, Kensuke Sasaki, Takao Masaki, Yusuke Suzuki, Tomoichiro Asano, Akifumi Kushiyama
Published 2018-12-01

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis

by Yasuka Matsunaga, Yusuke Nakatsu, Toshiaki Fukushima, Hirofumi Okubo, Misaki Iwashita, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Akifumi Kushiyama, Shin-ichiro Takahashi, Yoshihiro Tsuchiya, Hideaki Kamata, Fuminori Tokunaga, Kazuhiro Iwai, Tomoichiro Asano
Published 2015-01-01