Residue 6.43 defines receptor function in class F GPCRs

by Ainoleena Turku, Hannes Schihada, Pawel Kozielewicz, Carl-Fredrik Bowin, Gunnar Schulte
Published 2021-06-01

Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity.

by Ainoleena Turku, Maiju K Rinne, Gustav Boije Af Gennäs, Henri Xhaard, Dan Lindholm, Jyrki P Kukkonen
Published 2017-01-01

Insights into the mechanism of membrane pyrophosphatases by combining experiment and computer simulation

by Nita R. Shah, Craig Wilkinson, Steven P. D. Harborne, Ainoleena Turku, Kun-Mou Li, Yuh-Ju Sun, Sarah Harris, Adrian Goldman
Published 2017-05-01

Structural insight into small molecule action on Frizzleds

by Paweł Kozielewicz, Ainoleena Turku, Carl-Fredrik Bowin, Julian Petersen, Jana Valnohova, Maria Consuelo Alonso Cañizal, Yuki Ono, Asuka Inoue, Carsten Hoffmann, Gunnar Schulte
Published 2020-01-01

Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C.

by Riccardo Provenzani, Ilari Tarvainen, Giulia Brandoli, Antti Lempinen, Sanna Artes, Ainoleena Turku, Maria Helena Jäntti, Virpi Talman, Jari Yli-Kauhaluoma, Raimo K Tuominen, Gustav Boije Af Gennäs
Published 2018-01-01