Modulation of K(Ca)3.1 channels by eicosanoids, omega-3 fatty acids, and molecular determinants.

by Michael Kacik, Aida Oliván-Viguera, Ralf Köhler
Published 2014-01-01

Extracellular <span style="font-variant: small-caps">l</span>-arginine Enhances Relaxations Induced by Opening of Calcium-Activated SKCa Channels in Porcine Retinal Arteriole

by Ulf Simonsen, Anna K. Winther, Aida Oliván-Viguera, Simon Comerma-Steffensen, Ralf Köhler, Toke Bek
Published 2019-04-01

Novel phenolic inhibitors of small/intermediate-conductance Ca²⁺-activated K⁺ channels, KCa3.1 and KCa2.3.

by Aida Oliván-Viguera, Marta Sofía Valero, María Divina Murillo, Heike Wulff, Angel-Luis García-Otín, José-Miguel Arbonés-Mainar, Ralf Köhler
Published 2013-01-01

High expression of KCa3.1 in patients with clear cell renal carcinoma predicts high metastatic risk and poor survival.

by Maj Rabjerg, Aida Oliván-Viguera, Lars Koch Hansen, Line Jensen, Linda Sevelsted-Møller, Steen Walter, Boye L Jensen, Niels Marcussen, Ralf Köhler
Published 2015-01-01

Genetic KCa3.1-deficiency produces locomotor hyperactivity and alterations in cerebral monoamine levels.

by Kate Lykke Lambertsen, Jan Bert Gramsbergen, Mithula Sivasaravanaparan, Nicholas Ditzel, Linda Maria Sevelsted-Møller, Aida Oliván-Viguera, Maj Rabjerg, Heike Wulff, Ralf Köhler
Published 2012-01-01

Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes.

by Aida Olivan-Viguera, Angel Luis Garcia-Otin, Javier Lozano-Gerona, Edgar Abarca-Lachen, Ana J Garcia-Malinis, Kirk L Hamilton, Yolanda Gilaberte, Esther Pueyo, Ralf Köhler
Published 2018-01-01

KCa3.1 Transgene Induction in Murine Intestinal Epithelium Causes Duodenal Chyme Accumulation and Impairs Duodenal Contractility

by Marta Sofía Valero, Mariano Ramón-Gimenez, Javier Lozano-Gerona, Pablo Delgado-Wicke, Pilar Calmarza, Aida Oliván-Viguera, Víctor López, Ángel-Luis Garcia-Otín, Salvador Valero, Esther Pueyo, Kirk L. Hamilton, Hiroto Miura, Ralf Köhler
Published 2019-03-01

Tungstate-targeting of BKαβ1 channels tunes ERK phosphorylation and cell proliferation in human vascular smooth muscle.

by Ana Isabel Fernández-Mariño, Pilar Cidad, Delia Zafra, Laura Nocito, Jorge Domínguez, Aida Oliván-Viguera, Ralf Köhler, José R López-López, María Teresa Pérez-García, Miguel Ángel Valverde, Joan J Guinovart, José M Fernández-Fernández
Published 2015-01-01

Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis.

by Javier Lozano-Gerona, Aida Oliván-Viguera, Pablo Delgado-Wicke, Vikrant Singh, Brandon M Brown, Elena Tapia-Casellas, Esther Pueyo, Marta Sofía Valero, Ángel-Luis Garcia-Otín, Pilar Giraldo, Edgar Abarca-Lachen, Joaquín C Surra, Jesús Osada, Kirk L Hamilton, Siba P Raychaudhuri, Miguel Marigil, Ángeles Juarranz, Heike Wulff, Hiroto Miura, Yolanda Gilaberte, Ralf Köhler
Published 2020-01-01