Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1.

by Barbara Renga, Sabrina Cipriani, Adriana Carino, Michele Simonetti, Angela Zampella, Stefano Fiorucci
Published 2015-01-01

Bile Acids Activated Receptors in Inflammatory Bowel Disease

by Michele Biagioli, Silvia Marchianò, Adriana Carino, Cristina Di Giorgio, Luca Santucci, Eleonora Distrutti, Stefano Fiorucci
Published 2021-05-01

Divergent Effectiveness of Multispecies Probiotic Preparations on Intestinal Microbiota Structure Depends on Metabolic Properties

by Michele Biagioli, Daniela Capobianco, Adriana Carino, Silvia Marchianò, Chiara Fiorucci, Patrizia Ricci, Eleonora Distrutti, Stefano Fiorucci
Published 2019-02-01

Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation

by Michele Biagioli, Adriana Carino, Cristina Di Giorgio, Silvia Marchianò, Martina Bordoni, Rosalinda Roselli, Eleonora Distrutti, Stefano Fiorucci
Published 2020-06-01

Phallusiasterol C, A New Disulfated Steroid from the Mediterranean Tunicate Phallusia fumigata

by Concetta Imperatore, Maria Senese, Anna Aiello, Paolo Luciano, Stefano Fiorucci, Claudio D’Amore, Adriana Carino, Marialuisa Menna
Published 2016-06-01

Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity

by Michele Biagioli, Luca Laghi, Adriana Carino, Sabrina Cipriani, Eleonora Distrutti, Silvia Marchianò, Carola Parolin, Paolo Scarpelli, Beatrice Vitali, Stefano Fiorucci
Published 2017-07-01

Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential

by Adriana Carino, Luigina Graziosi, Silvia Marchianò, Michele Biagioli, Elisabetta Marino, Valentina Sepe, Angela Zampella, Eleonora Distrutti, Annibale Donini, Stefano Fiorucci
Published 2021-05-01

The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation.

by Barbara Renga, Andrea Mencarelli, Sabrina Cipriani, Claudio D'Amore, Adriana Carino, Angela Bruno, Daniela Francisci, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci
Published 2013-01-01

Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties

by Claudia Finamore, Giuliana Baronissi, Silvia Marchianò, Francesco Saverio Di Leva, Adriana Carino, Maria Chiara Monti, Vittorio Limongelli, Angela Zampella, Stefano Fiorucci, Valentina Sepe
Published 2019-03-01

Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling.

by Sabrina Cipriani, Barbara Renga, Claudio D'Amore, Michele Simonetti, Antonio Angelo De Tursi, Adriana Carino, Maria Chiara Monti, Valentina Sepe, Angela Zampella, Stefano Fiorucci
Published 2015-01-01

GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated HepatitisSummary

by Michele Biagioli, Adriana Carino, Chiara Fiorucci, Silvia Marchianò, Cristina Di Giorgio, Rosalinda Roselli, Margherita Magro, Eleonora Distrutti, Oxana Bereshchenko, Paolo Scarpelli, Angela Zampella, Stefano Fiorucci
Published 2019-01-01

Solomonsterol A, a Marine Pregnane-X-Receptor Agonist, Attenuates Inflammation and Immune Dysfunction in a Mouse Model of Arthritis

by Andrea Mencarelli, Claudio D'Amore, Barbara Renga, Sabrina Cipriani, Adriana Carino, Valentina Sepe, Elisa Perissutti, Maria Valeria D'Auria, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci
Published 2013-12-01

Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain

by Adriana Carino, Federica Moraca, Federica Moraca, Bianca Fiorillo, Silvia Marchianò, Valentina Sepe, Michele Biagioli, Claudia Finamore, Silvia Bozza, Daniela Francisci, Eleonora Distrutti, Bruno Catalanotti, Angela Zampella, Stefano Fiorucci
Published 2020-10-01

The HIV matrix protein p17 promotes the activation of human hepatic stellate cells through interactions with CXCR2 and Syndecan-2.

by Barbara Renga, Daniela Francisci, Elisabetta Schiaroli, Adriana Carino, Sabrina Cipriani, Claudio D'Amore, Angelo Sidoni, Rachele Del Sordo, Ivana Ferri, Monica Lucattelli, Benedetta Lunghi, Franco Baldelli, Stefano Fiorucci
Published 2014-01-01

Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation

by Adriana Carino, Silvia Marchianò, Michele Biagioli, Chiara Fiorucci, Angela Zampella, Maria Chiara Monti, Elva Morretta, Martina Bordoni, Cristina Di Giorgio, Rosalinda Roselli, Patrizia Ricci, Eleonora Distrutti, Stefano Fiorucci
Published 2019-05-01

The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions

by Michele Biagioli, Adriana Carino, Chiara Fiorucci, Giannamaria Annunziato, Silvia Marchianò, Martina Bordoni, Rosalinda Roselli, Cristina Di Giorgio, Federica Castiglione, Patrizia Ricci, Agostino Bruno, Andrea Faccini, Eleonora Distrutti, Monia Baldoni, Gabriele Costantino, Stefano Fiorucci
Published 2019-08-01