Production of IFN-γ by splenic dendritic cells during innate immune responses against Francisella tularensis LVS depends on MyD88, but not TLR2, TLR4, or TLR9.

by Roberto De Pascalis, Amy P Rossi, Lara Mittereder, Kazuyo Takeda, Adovi Akue, Sherry L Kurtz, Karen L Elkins
Published 2020-01-01

Memory CD73+IgM+ B cells protect against Plasmodium yoelii infection and express Granzyme B.

by Marcela Parra, Megan Weitner, Amy Yang, Adovi Akue, Xia Liu, Thomas Schmidt, Windy R Allman, Mustafa Akkoyunlu, Steven C Derrick
Published 2020-01-01

BRAF and MEK inhibitors differentially affect nivolumab-induced T cell activation by modulating the TCR and AKT signaling pathways

by Peng Yue, Taylor Harper, Silvia M. Bacot, Monica Chowdhury, Shiowjen Lee, Adovi Akue, Mark A. Kukuruga, Tao Wang, Gerald M. Feldman
Published 2019-01-01

Exploring the Potential Use of a PBMC-Based Functional Assay to Identify Predictive Biomarkers for Anti-PD-1 Immunotherapy

by Silvia M. Bacot, Taylor A. Harper, Rebecca L. Matthews, Christie Jane Fennell, Adovi Akue, Mark A. KuKuruga, Shiowjen Lee, Tao Wang, Gerald M. Feldman
Published 2020-11-01

TCRβ-expressing macrophages induced by a pathogenic murine malaria correlate with parasite burden and enhanced phagocytic activity.

by Miranda S Oakley, Joanna K Chorazeczewski, Maya Aleshnick, Vivek Anantharaman, Victoria Majam, Bhavna Chawla, Timothy G Myers, Qin Su, Winter A Okoth, Kazuyo Takeda, Adovi Akue, Mark KuKuruga, L Aravind, Sanjai Kumar
Published 2018-01-01