Regulating IRFs in IFN Driven Disease

by Caroline A. Jefferies
Published 2019-03-01

Tweeters and Woofers: The Complex Orchestra of Calcium Currents in T Lymphocytes

by Lilian L Nohara, Lilian L Nohara, Shawna R Stanwood, Shawna R Stanwood, Kyla D Omilusik, Kyla D Omilusik, Kyla D Omilusik, Wilfred A Jefferies, Wilfred A Jefferies, Wilfred A Jefferies, Wilfred A Jefferies, Wilfred A Jefferies, Wilfred A Jefferies
Published 2015-05-01

Tyrosine phosphorylation of the E3 ubiquitin ligase TRIM21 positively regulates interaction with IRF3 and hence TRIM21 activity.

by Kevin B Stacey, Eamon Breen, Caroline A Jefferies
Published 2012-01-01

Dendritic cell cross-priming is essential for immune responses to Listeria monocytogenes.

by Anna T Reinicke, Kyla D Omilusik, Genc Basha, Wilfred A Jefferies
Published 2009-10-01

Discovery of a Highly Conserved Peptide in the Iron Transporter Melanotransferrin that Traverses an Intact Blood Brain Barrier and Localizes in Neural Cells

by Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Brett A. Eyford, Brett A. Eyford, Brett A. Eyford, Brett A. Eyford, Thomas Abraham, Lonna Munro, Lonna Munro, Lonna Munro, Lonna Munro, Kyung Bok Choi, Kyung Bok Choi, Kyung Bok Choi, Kyung Bok Choi, Mark Okon, Timothy Z. Vitalis, Reinhard Gabathuler, Reinhard Gabathuler, Chieh-Ju Lu, Chieh-Ju Lu, Chieh-Ju Lu, Chieh-Ju Lu, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies
Published 2021-06-01

Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease.

by Kaan E Biron, Dara L Dickstein, Rayshad Gopaul, Wilfred A Jefferies
Published 2011-01-01

Mutation of an L-Type Calcium Channel Gene Leads to T Lymphocyte Dysfunction

by Franz Fenninger, Franz Fenninger, Franz Fenninger, Franz Fenninger, Franz Fenninger, Jeffrey Han, Shawna R. Stanwood, Shawna R. Stanwood, Shawna R. Stanwood, Shawna R. Stanwood, Shawna R. Stanwood, Lilian L. Nohara, Lilian L. Nohara, Lilian L. Nohara, Hitesh Arora, Hitesh Arora, Hitesh Arora, Hitesh Arora, Hitesh Arora, Kyung Bok Choi, Kyung Bok Choi, Kyung Bok Choi, Kyung Bok Choi, Lonna Munro, Lonna Munro, Lonna Munro, Lonna Munro, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Iryna Shanina, Marc S. Horwitz, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies
Published 2019-10-01

A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke

by Brett A. Eyford, Brett A. Eyford, Brett A. Eyford, Brett A. Eyford, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Thomas Abraham, Lonna Munro, Lonna Munro, Kyung Bok Choi, Kyung Bok Choi, Tracy Hill, Rhonda Hildebrandt, Ian Welch, Timothy Z. Vitalis, Reinhard Gabathuler, Reinhard Gabathuler, Jacob A. Gordon, Jacob A. Gordon, Hans Adomat, Hans Adomat, Emma S.T. Guns, Emma S.T. Guns, Chieh-Ju Lu, Chieh-Ju Lu, Chieh-Ju Lu, Chieh-Ju Lu, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies
Published 2021-03-01

Corrigendum: A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke

by Brett A. Eyford, Brett A. Eyford, Brett A. Eyford, Brett A. Eyford, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Thomas Abraham, Lonna Munro, Lonna Munro, Kyung Bok Choi, Kyung Bok Choi, Tracy Hill, Rhonda Hildebrandt, Ian Welch, Timothy Z. Vitalis, Timothy Z. Vitalis, Reinhard Gabathuler, Reinhard Gabathuler, Jacob A. Gordon, Jacob A. Gordon, Hans Adomat, Hans Adomat, Emma S.T. Guns, Emma S.T. Guns, Chieh-Ju Lu, Chieh-Ju Lu, Chieh-Ju Lu, Chieh-Ju Lu, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies
Published 2021-05-01

Macrophage MMP10 Regulates TLR7-Mediated Tolerance

by Maryam G. Rohani, Elizabeth Dimitrova, Andrew Beppu, Ying Wang, Caroline A. Jefferies, William C. Parks
Published 2018-12-01

MHC class I endosomal and lysosomal trafficking coincides with exogenous antigen loading in dendritic cells.

by Genc Basha, Gregory Lizée, Anna T Reinicke, Robyn P Seipp, Kyla D Omilusik, Wilfred A Jefferies
Published 2008-01-01

TRIpartite motif 21 (TRIM21) differentially regulates the stability of interferon regulatory factor 5 (IRF5) isoforms.

by Elisa Lazzari, Justyna Korczeniewska, Joan Ní Gabhann, Siobhán Smith, Betsy J Barnes, Caroline A Jefferies
Published 2014-01-01

Herpes simplex virus 1 targets IRF7 via ICP0 to limit type I IFN induction

by David Shahnazaryan, Rana Khalil, Claire Wynne, Caroline A. Jefferies, Joan Ní Gabhann-Dromgoole, Conor C. Murphy
Published 2020-12-01

Bleeding is increased in amyloid precursor protein knockout mouse

by Nima Mazinani, Amy W. Strilchuk, James R. Baylis, Woosuk S. Hur, Wilfred A. Jefferies, Christian J. Kastrup
Published 2020-07-01

Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors.

by Rowan Higgs, Elisa Lazzari, Claire Wynne, Joan Ní Gabhann, Alexander Espinosa, Marie Wahren-Herlenius, Caroline A Jefferies
Published 2010-01-01

Reversing pathology in a preclinical model of Alzheimer's disease by hacking cerebrovascular neoangiogenesis with advanced cancer therapeutics

by Chaahat S.B. Singh, Kyung Bok Choi, Lonna Munro, Hong Yue Wang, Cheryl G. Pfeifer, Wilfred A. Jefferies
Published 2021-09-01

Genetics of SLE: Functional Relevance for Monocytes/Macrophages in Disease

by Jennifer C. Byrne, Joan Ní Gabhann, Elisa Lazzari, Rebecca Mahony, Siobhán Smith, Kevin Stacey, Claire Wynne, Caroline A. Jefferies
Published 2012-01-01

Serum free culture for the expansion and study of type 2 innate lymphoid cells

by Pablo de Lucía Finkel, Christopher Sherwood, Iryna Saranchova, Wenjing Xia, Lonna Munro, Cheryl G. Pfeifer, James M. Piret, Wilfred A. Jefferies
Published 2021-06-01

Correction: A Unique Carrier for Delivery of Therapeutic Compounds beyond the Blood-Brain Barrier

by Delara Karkan, Cheryl Pfeifer, Timothy Z. Vitalis, Gavin Arthur, Maki Ujiie, Qingqi Chen, Sam Tsai, Gerrasimo Koliatis, Reinhard Gabathuler, Wilfred A. Jefferies
Published 2008-01-01

Correction: A Unique Carrier for Delivery of Therapeutic Compounds beyond the Blood-Brain Barrier

by Delara Karkan, Cheryl Pfeifer, Timothy Z. Vitalis, Gavin Arthur, Maki Ujiie, Qingqi Chen, Sam Tsai, Gerrasimo Koliatis, Reinhard Gabathuler, Wilfred A. Jefferies
Published 2008-01-01