Uncovering cancer vulnerabilities by machine learning prediction of synthetic lethality

by Salvatore Benfatto, Özdemirhan Serçin, Francesca R. Dejure, Amir Abdollahi, Frank T. Zenke, Balca R. Mardin
Published 2021-08-01

A scalable CRISPR/Cas9-based fluorescent reporter assay to study DNA double-strand break repair choice

by Paris Roidos, Stephanie Sungalee, Salvatore Benfatto, Özdemirhan Serçin, Adrian M. Stütz, Amir Abdollahi, Jan Mauer, Frank T. Zenke, Jan O. Korbel, Balca R. Mardin
Published 2020-08-01

Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells

by Alexandros P. Drainas, Ruxandra A. Lambuta, Irina Ivanova, Özdemirhan Serçin, Ioannis Sarropoulos, Mike L. Smith, Theocharis Efthymiopoulos, Benjamin Raeder, Adrian M. Stütz, Sebastian M. Waszak, Balca R. Mardin, Jan O. Korbel
Published 2020-04-01

A solid‐phase transfection platform for arrayed CRISPR screens

by Özdemirhan Serçin, Sabine Reither, Paris Roidos, Nadja Ballin, Spyridon Palikyras, Anna Baginska, Katrin Rein, Maria Llamazares, Aliaksandr Halavatyi, Hauke Winter, Thomas Muley, Renata Z Jurkowska, Amir Abdollahi, Frank T Zenke, Beate Neumann, Balca R Mardin
Published 2020-06-01

A solid‐phase transfection platform for arrayed CRISPR screens

by Özdemirhan Serçin, Sabine Reither, Paris Roidos, Nadja Ballin, Spyridon Palikyras, Anna Baginska, Katrin Rein, Maria Llamazares, Aliaksandr Halavatyi, Hauke Winter, Thomas Muley, Renata Z Jurkowska, Amir Abdollahi, Frank T Zenke, Beate Neumann, Balca R Mardin
Published 2019-12-01