The HIV-1 Accessory Protein Vpu Downregulates Peroxisome Biogenesis

by Zaikun Xu, Robert Lodge, Christopher Power, Eric A. Cohen, Tom C. Hobman
Published 2020-03-01

Remodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and Persistence

by Scott M. Sugden, Mariana G. Bego, Tram N.Q. Pham, Éric A. Cohen
Published 2016-03-01

HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase.

by Jean-Philippe Belzile, Ghislaine Duisit, Nicole Rougeau, Johanne Mercier, Andrés Finzi, Eric A Cohen
Published 2007-07-01

Vpu Exploits the Cross-Talk between BST2 and the ILT7 Receptor to Suppress Anti-HIV-1 Responses by Plasmacytoid Dendritic Cells.

by Mariana G Bego, Édouard Côté, Nick Aschman, Johanne Mercier, Winfried Weissenhorn, Éric A Cohen
Published 2015-07-01

miRNA-1236 inhibits HIV-1 infection of monocytes by repressing translation of cellular factor VprBP.

by Li Ma, Chan-Juan Shen, Éric A Cohen, Si-Dong Xiong, Jian-Hua Wang
Published 2014-01-01

Formation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrest.

by Jean-Philippe Belzile, Levon G Abrahamyan, Francine C A Gérard, Nicole Rougeau, Eric A Cohen
Published 2010-09-01

Regulation of CD4 Receptor and HIV-1 Entry by MicroRNAs-221 and -222 during Differentiation of THP-1 Cells

by Robert Lodge, Julian C. Gilmore, Jérémy A. Ferreira Barbosa, Félix Lombard-Vadnais, Éric A. Cohen
Published 2017-12-01

Dual mechanisms of translation initiation of the full-length HIV-1 mRNA contribute to gag synthesis.

by Anne Monette, Fernando Valiente-Echeverría, Matias Rivero, Éric A Cohen, Marcelo Lopez-Lastra, Andrew J Mouland
Published 2013-01-01

Antagonism of tetherin restriction of HIV-1 release by Vpu involves binding and sequestration of the restriction factor in a perinuclear compartment.

by Mathieu Dubé, Bibhuti Bhusan Roy, Pierre Guiot-Guillain, Julie Binette, Johanne Mercier, Antoine Chiasson, Eric A Cohen
Published 2010-04-01

Defining the interactions and role of DCAF1/VPRBP in the DDB1-cullin4A E3 ubiquitin ligase complex engaged by HIV-1 Vpr to induce a G2 cell cycle arrest.

by Francine C A Gérard, Ruifeng Yang, Bizhan Romani, Alexis Poisson, Jean-Philippe Belzile, Nicole Rougeau, Éric A Cohen
Published 2014-01-01

Incorporation of Ebola glycoprotein into HIV particles facilitates dendritic cell and macrophage targeting and enhances HIV-specific immune responses.

by Zhujun Ao, Lijun Wang, Emelissa J Mendoza, Keding Cheng, Wenjun Zhu, Eric A Cohen, Keith Fowke, Xiangguo Qiu, Gary Kobinger, Xiaojian Yao
Published 2019-01-01

Hepatitis C virus core protein induces neuroimmune activation and potentiates Human Immunodeficiency Virus-1 neurotoxicity.

by Pornpun Vivithanaporn, Ferdinand Maingat, Liang-Tzung Lin, Hong Na, Christopher D Richardson, Babita Agrawal, Eric A Cohen, Jack H Jhamandas, Christopher Power
Published 2010-09-01

L-Carnitine Tartrate Downregulates the ACE2 Receptor and Limits SARS-CoV-2 Infection

by Aouatef Bellamine, Tram N. Q. Pham, Jaspreet Jain, Jacob Wilson, Kazim Sahin, Frederic Dallaire, Nabil G. Seidah, Shane Durkee, Katarina Radošević, Éric A. Cohen
Published 2021-04-01

The evaluation of risk-benefit ratio for gut tissue sampling in HIV cure research

by Vikram Mehraj, Peter Ghali, Rayoun Ramendra, Cecilia Costiniuk, Bertrand Lebouché, Rosalie Ponte, Robert Reinhard, Jose Sousa, Nicolas Chomont, Eric A. Cohen, Petronela Ancuta, Jean-Pierre Routy
Published 2017-10-01

USP18 is a significant driver of memory CD4 T-cell reduced viability caused by type I IFN signaling during primary HIV-1 infection.

by Xavier Dagenais-Lussier, Hamza Loucif, Hugo Cadorel, Juliette Blumberger, Stéphane Isnard, Mariana Gé Bego, Éric A Cohen, Jean-Pierre Routy, Julien van Grevenynghe, Montreal Primary Infection Study Group
Published 2019-10-01

Naturally-occurring genetic variants in human DC-SIGN increase HIV-1 capture, cell-transfer and risk of mother-to-child transmission.

by Geneviève Boily-Larouche, Miroslav P Milev, Lynn S Zijenah, Annie-Claude Labbé, Djimon M Zannou, Jean H Humphrey, Brian J Ward, Johanne Poudrier, Andrew J Mouland, Eric A Cohen, Michel Roger
Published 2012-01-01

Flt3L-Mediated Expansion of Plasmacytoid Dendritic Cells Suppresses HIV Infection in Humanized Mice

by Tram N.Q. Pham, Oussama Meziane, Mohammad Alam Miah, Olga Volodina, Chloé Colas, Kathie Béland, Yuanyi Li, Frédéric Dallaire, Tibor Keler, Jean V. Guimond, Sylvie Lesage, Cheolho Cheong, Élie Haddad, Éric A. Cohen
Published 2019-11-01

Reduced antiretroviral drug efficacy and concentration in HIV-infected microglia contributes to viral persistence in brain

by Eugene L. Asahchop, Oussama Meziane, Manmeet K. Mamik, Wing F. Chan, William G. Branton, Lothar Resch, M. John Gill, Elie Haddad, Jean V. Guimond, Mark A. Wainberg, Glen B. Baker, Eric A. Cohen, Christopher Power
Published 2017-10-01

Host MicroRNAs-221 and -222 Inhibit HIV-1 Entry in Macrophages by Targeting the CD4 Viral Receptor

by Robert Lodge, Jérémy A. Ferreira Barbosa, Félix Lombard-Vadnais, Julian C. Gilmore, Alexandre Deshiere, Annie Gosselin, Tomas Raul Wiche Salinas, Mariana G. Bego, Christopher Power, Jean-Pierre Routy, Petronela Ancuta, Michel J. Tremblay, Éric A. Cohen
Published 2017-10-01

Combining radiomic phenotypes of non-small cell lung cancer with liquid biopsy data may improve prediction of response to EGFR inhibitors

by Bardia Yousefi, Michael J. LaRiviere, Eric A. Cohen, Thomas H. Buckingham, Stephanie S. Yee, Taylor A. Black, Austin L. Chien, Peter Noël, Wei-Ting Hwang, Sharyn I. Katz, Charu Aggarwal, Jeffrey C. Thompson, Erica L. Carpenter, Despina Kontos
Published 2021-05-01