Alkaloid and acetogenin-rich fraction from Annona crassiflora fruit peel inhibits proliferation and migration of human liver cancer HepG2 cells.

by Allisson B Justino, Rodrigo M Florentino, Andressa França, Antonio C M L Filho, Rodrigo R Franco, André L Saraiva, Matheus C Fonseca, Maria F Leite, Foued Salmen Espindola
Published 2021-01-01

Is HSD17B13 Genetic Variant a Protector for Liver Dysfunction? Future Perspective as a Potential Therapeutic Target

by Takashi Motomura, Sriram Amirneni, Ricardo Diaz-Aragon, Lanuza A. P. Faccioli, Michelle R. Malizio, Michael C. Coard, Zehra N. Kocas-Kilicarslan, Carla Frau, Nils Haep, Alina Ostrowska, Rodrigo M. Florentino, Alejandro Soto-Gutierrez
Published 2021-06-01

Polymorphism in the Promoter Region of NFE2L2 Gene Is a Genetic Marker of Susceptibility to Cirrhosis Associated with Alcohol Abuse

by Kemper Nunes dos Santos, Rodrigo M. Florentino, Andressa França, Antônio Carlos Melo Lima Filho, Marcone Loiola dos Santos, Dabny Missiaggia, Matheus de Castro Fonseca, Igor Brasil Costa, Paula Vieira Teixeira Vidigal, Michael H. Nathanson, Fernanda de Oliveira Lemos, M. Fatima Leite
Published 2019-07-01

Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells

by Kazuki Takeishi, Alexandra Collin de l’Hortet, Yang Wang, Kan Handa, Jorge Guzman-Lepe, Kentaro Matsubara, Kazutoyo Morita, Sae Jang, Nils Haep, Rodrigo M. Florentino, Fangchao Yuan, Ken Fukumitsu, Kimimasa Tobita, Wendell Sun, Jonathan Franks, Evan R. Delgado, Erik M. Shapiro, Nicolas A. Fraunhoffer, Andrew W. Duncan, Hiroshi Yagi, Tomoji Mashimo, Ira J. Fox, Alejandro Soto-Gutierrez
Published 2020-06-01

Cellular Location of HNF4α is Linked With Terminal Liver Failure in Humans

by Rodrigo M. Florentino, Nicolas A. Fraunhoffer, Kazutoyo Morita, Kazuki Takeishi, Alina Ostrowska, Abhinav Achreja, Olamide Animasahun, Nils Haep, Shohrat Arazov, Nandini Agarwal, Alexandra Collin de l'Hortet, Jorge Guzman‐Lepe, Edgar N. Tafaleng, Amitava Mukherjee, Kris Troy, Swati Banerjee, Shirish Paranjpe, George K. Michalopoulos, Aaron Bell, Deepak Nagrath, Sarah J. Hainer, Ira J. Fox, Alejandro Soto‐Gutierrez
Published 2020-06-01

Molecular Mechanism for Protection Against Liver Failure in Human Yellow Fever Infection

by Fernanda de Oliveira Lemos, Andressa França, Antônio Carlos Melo Lima Filho, Rodrigo M. Florentino, Marcone Loiola Santos, Dabny G. Missiaggia, Gisele Olinto Libanio Rodrigues, Felipe Ferraz Dias, Ingredy Beatriz Souza Passos, Mauro M. Teixeira, Antônio Márcio de Faria Andrade, Cristiano Xavier Lima, Paula Vieira Teixeira Vidigal, Vivian Vasconcelos Costa, Matheus Castro Fonseca, Michael H. Nathanson, M. Fatima Leite
Published 2020-05-01