Arsenic trioxide overcomes rapamycin-induced feedback activation of AKT and ERK signaling to enhance the anti-tumor effects in breast cancer.

by Cynthia Guilbert, Matthew G Annis, Zhifeng Dong, Peter M Siegel, Wilson H Miller, Koren K Mann
Published 2013-01-01

ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties.

by April A N Rose, Matthew G Annis, Zhifeng Dong, Francois Pepin, Michael Hallett, Morag Park, Peter M Siegel
Published 2010-08-01

Integrin-uPAR signaling leads to FRA-1 phosphorylation and enhanced breast cancer invasion

by Matthew G. Annis, Veronique Ouellet, Jonathan P. Rennhack, Sylvain L’Esperance, Claudine Rancourt, Anne-Marie Mes-Masson, Eran R. Andrechek, Peter M. Siegel
Published 2018-01-01

Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer

by Shawn McGuirk, Yannick Audet-Delage, Matthew G Annis, Yibo Xue, Mathieu Vernier, Kaiqiong Zhao, Catherine St-Louis, Lucía Minarrieta, David A Patten, Geneviève Morin, Celia MT Greenwood, Vincent Giguère, Sidong Huang, Peter M Siegel, Julie St-Pierre
Published 2021-06-01

Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis

by Brian E. Hsu, Sébastien Tabariès, Radia M. Johnson, Sylvia Andrzejewski, Julien Senecal, Camille Lehuédé, Matthew G. Annis, Eric H. Ma, Sandra Völs, LeeAnn Ramsay, Remi Froment, Anie Monast, Ian R. Watson, Zvi Granot, Russell G. Jones, Julie St-Pierre, Peter M. Siegel
Published 2019-06-01

p66ShcA functions as a contextual promoter of breast cancer metastasis

by Kyle Lewis, Alex Kiepas, Jesse Hudson, Julien Senecal, Jacqueline R. Ha, Elena Voorand, Matthew G. Annis, Valerie Sabourin, Ryuhjin Ahn, Rachel La Selva, Sébastien Tabariès, Brian E. Hsu, Matthew J. Siegel, Matthew Dankner, Eduardo Cepeda Canedo, Mathieu Lajoie, Ian R. Watson, Claire M. Brown, Peter M. Siegel, Josie Ursini-Siegel
Published 2020-01-01

Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern

by Sébastien Tabariès, Matthew G. Annis, Anthoula Lazaris, Stephanie K. Petrillo, Jennifer Huxham, Amri Abdellatif, Vincent Palmieri, Jaclyn Chabot, Radia M. Johnson, Steven Van Laere, Cornelis Verhoef, Yasmina Hachem, Sara Yumeen, Nicholas Meti, Atilla Omeroglu, Gulbeyaz Altinel, Zu-Hua Gao, Alan S. L. Yu, Dirk J. Grünhagen, Peter Vermeulen, Peter Metrakos, Peter M. Siegel
Published 2021-06-01