Highly Selective and Tunable Protein Hydrolysis by a Polyoxometalate Complex in Surfactant Solutions: A Step toward the Development of Artificial Metalloproteases for Membrane Prot...

by Annelies Sap, Laurens Vandebroek, Vincent Goovaerts, Erik Martens, Paul Proost, Tatjana N. Parac-Vogt
Published 2017-05-01

Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study.

by Jennifer Vandooren, Sofie Knoops, João L Aldinucci Buzzo, Lise Boon, Erik Martens, Ghislain Opdenakker, Elzbieta Kolaczkowska
Published 2017-01-01

MMP-9/Gelatinase B Degrades Immune Complexes in Systemic Lupus Erythematosus

by Estefania Ugarte-Berzal, Lise Boon, Erik Martens, Vasily Rybakin, Daniel Blockmans, Jennifer Vandooren, Paul Proost, Ghislain Opdenakker
Published 2019-03-01

Interference with glycosaminoglycan-chemokine interactions with a probe to alter leukocyte recruitment and inflammation in vivo.

by Sandra Li, Ulrika S Pettersson, Bart Hoorelbeke, Elzbieta Kolaczkowska, Katrien Schelfhout, Erik Martens, Paul Kubes, Jo Van Damme, Mia Phillipson, Ghislain Opdenakker
Published 2014-01-01

Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis.

by Estefania Ugarte-Berzal, Nele Berghmans, Lise Boon, Erik Martens, Jennifer Vandooren, Bénédicte Cauwe, Greet Thijs, Paul Proost, Jo Van Damme, Ghislain Opdenakker
Published 2018-01-01

Insufficiently defined genetic background confounds phenotypes in transgenic studies as exemplified by malaria infection in Tlr9 knockout mice.

by Nathalie Geurts, Erik Martens, Sebastien Verhenne, Natacha Lays, Greet Thijs, Stefan Magez, Bénédicte Cauwe, Sandra Li, Hubertine Heremans, Ghislain Opdenakker, Philippe E Van den Steen
Published 2011-01-01

Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms

by Elisa Nuti, Armando Rossello, Doretta Cuffaro, Caterina Camodeca, Jens Van Bael, Dries van der Maat, Erik Martens, Pierre Fiten, Rafaela Vaz Sousa Pereira, Estefania Ugarte-Berzal, Mieke Gouwy, Ghislain Opdenakker, Jennifer Vandooren
Published 2020-07-01

The Biological Potential Hidden in Inclusion Bodies

by Laia Gifre-Renom, Joaquin Seras-Franzoso, Diana Rafael, Fernanda Andrade, Olivia Cano-Garrido, Francesc Martinez-Trucharte, Estefania Ugarte-Berzal, Erik Martens, Lise Boon, Antonio Villaverde, Ghislain Opdenakker, Simó Schwartz, Anna Arís, Elena Garcia-Fruitós
Published 2020-02-01

Recombinant Protein-Based Nanoparticles: Elucidating their Inflammatory Effects In Vivo and their Potential as a New Therapeutic Format

by Laia Gifre-Renom, Estefania Ugarte-Berzal, Erik Martens, Lise Boon, Olivia Cano-Garrido, Esther Martínez-Núñez, Teresa Luque, Ramon Roca-Pinilla, Òscar Conchillo-Solé, Neus Ferrer-Miralles, Antonio Villaverde, Ghislain Opdenakker, Elena Garcia-Fruitós, Anna Arís
Published 2020-05-01

From ELISA to Immunosorbent Tandem Mass Spectrometry Proteoform Analysis: The Example of CXCL8/Interleukin-8

by Mieke Metzemaekers, Sara Abouelasrar Salama, Jennifer Vandooren, Anneleen Mortier, Rik Janssens, Sofie Vandendriessche, Eva Ganseman, Erik Martens, Mieke Gouwy, Barbara Neerinckx, Patrick Verschueren, Lien De Somer, Carine Wouters, Sofie Struyf, Ghislain Opdenakker, Jo Van Damme, Paul Proost
Published 2021-03-01

Kinetics of peripheral blood neutrophils in severe coronavirus disease 2019

by Mieke Metzemaekers, Seppe Cambier, Marfa Blanter, Jennifer Vandooren, Ana Carolina deCarvalho, Bert Malengier‐Devlies, Lore Vanderbeke, Cato Jacobs, Sofie Coenen, Erik Martens, Noëmie Pörtner, Lotte Vanbrabant, Pierre Van Mol, Yannick Van Herck, Nathalie Van Aerde, Greet Hermans, Jan Gunst, Alexandre Borin, Bruna Toledo N Pereira, Arilson Bernardo dosSP Gomes, Stéfanie Primon Muraro, Gabriela Fabiano de Souza, Alessandro S Farias, José Luiz Proenca‐Modena, Marco Aurélio R Vinolo, the CONTAGIOUS Consortium, Pedro Elias Marques, Carine Wouters, Els Wauters, Sofie Struyf, Patrick Matthys, Ghislain Opdenakker, Rafael Elias Marques, Joost Wauters, Mieke Gouwy, Paul Proost
Published 2021-01-01

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

by Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne J. F. Kaptein, Rong Li, Valentijn Vergote, Laura Seldeslachts, Johan Van Weyenbergh, Carolien De Keyzer, Lindsey Bervoets, Sapna Sharma, Laurens Liesenborghs, Ji Ma, Sander Jansen, Dominique Van Looveren, Thomas Vercruysse, Xinyu Wang, Dirk Jochmans, Erik Martens, Kenny Roose, Dorien De Vlieger, Bert Schepens, Tina Van Buyten, Sofie Jacobs, Yanan Liu, Joan Martí-Carreras, Bert Vanmechelen, Tony Wawina-Bokalanga, Leen Delang, Joana Rocha-Pereira, Lotte Coelmont, Winston Chiu, Pieter Leyssen, Elisabeth Heylen, Dominique Schols, Lanjiao Wang, Lila Close, Jelle Matthijnssens, Marc Van Ranst, Veerle Compernolle, Georg Schramm, Koen Van Laere, Xavier Saelens, Nico Callewaert, Ghislain Opdenakker, Piet Maes, Birgit Weynand, Christopher Cawthorne, Greetje Vande Velde, Zhongde Wang, Johan Neyts, Kai Dallmeier
Published 2020-11-01