RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition

by Ting Jin, Hugo Lavoie, Malha Sahmi, Maud David, Christine Hilt, Amy Hammell, Marc Therrien
Published 2017-10-01

Novel natural inhibitors targeting B-RAF(V600E) by computational study

by Bo Wu, Zhiyun Zhang, Gaojing Dou, Xiaye Lv, Junliang Ge, Hongyu Wang, Haoqun Xie, Dong Zhu
Published 2021-01-01

Effects of 5-fluorouracil on biological characteristics and drug resistance mechanisms of liver cancer cell line PLC/RAF/5

by CHENG Kangwen, LI Qi, ZHAN Yongqiang
Published 2015-09-01

Polycomb group protein Bmi1 is required for growth of RAF driven non-small-cell lung cancer.

by Matthias Becker, Christian Korn, Arnold R Sienerth, Robert Voswinckel, Katharina Luetkenhaus, Fatih Ceteci, Ulf R Rapp
Published 2009-01-01

Molecular modeling, dynamics simulations, and binding efficiency of berberine derivatives: A new group of RAF inhibitors for cancer treatment.

by Parham Jabbarzadeh Kaboli, Patimah Ismail, King-Hwa Ling
Published 2018-01-01

MiRNA-424(322)-5p promotes corneal neovascularization in rats via activating Raf/MEK/ERK pathways

by CAO Lang, LI Xue, ZHOU Shanbi, WANG Hao
Published 2021-09-01

Studies on [5,6]-Fused Bicyclic Scaffolds Derivatives as Potent Dual B-RafV600E/KDR Inhibitors Using Docking and 3D-QSAR Approaches

by Hai-Chun Liu, San-Zhi Tang, Shuai Lu, Ting Ran, Jian Wang, Yan-Min Zhang, An-Yang Xu, Tao Lu, Ya-Dong Chen
Published 2015-10-01

Imidazothiazole-based potent inhibitors of V600E-B-RAF kinase with promising anti-melanoma activity: biological and computational studies

by Hanan S. Anbar, Mohammed I. El-Gamal, Hamadeh Tarazi, Bong S. Lee, Hong R. Jeon, Dow Kwon, Chang-Hyun Oh
Published 2020-01-01

Oxaliplatin Promotes Apoptosis of Gastric Cancer Cell Line SGC-7901 by Regulating miRNA-7-5p/RAF-1

by GU Zehui, REN Liqun, LI Qi, WANG Yadi, TAN Qi, LOU Xiaoqian, CHEN Suxian
Published 2020-03-01

FEODALISME DALAM NOVEL PIPISAHAN KARYA RAF

by Resti Nurfaidah
Published 2015-03-01

KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation

by Timothy H. Tran, Albert H. Chan, Lucy C. Young, Lakshman Bindu, Chris Neale, Simon Messing, Srisathiyanarayanan Dharmaiah, Troy Taylor, John-Paul Denson, Dominic Esposito, Dwight V. Nissley, Andrew G. Stephen, Frank McCormick, Dhirendra K. Simanshu
Published 2021-02-01

V-Raf murine sarcoma viral oncogene homolog B1 (BRAF) as a prognostic biomarker of poor outcomes in esophageal cancer patients

by Aihemaijiang Kuerbanjiang, Maimaitiyiming Maimaituerxun, Yanjun Zhang, Yiliang Li, Gang Cui, Aibaidula Abuduhabaier, Abuduwaili Aierken, Buya Miranbieke, Meilikezati Anzaer, Yusufu Maimaiti
Published 2021-02-01

B-Raf specific antibody responses in melanoma patients

by Vetter Claudia S, Heimbach Veronika, Potapenko Tamara, Becker Jürgen C, Fensterle Joachim, Bröcker Eva B, Rapp Ulf R
Published 2004-09-01

Raf kinases in signal transduction and interaction with translation machinery

by Migliaccio Nunzia, Sanges Carmen, Ruggiero Immacolata, Martucci Nicola M., Rippa Emilia, Arcari Paolo, Lamberti Annalisa
Published 2013-08-01

Purification of A-Raf and structural studies of mannitol dehydrogenase

by Puttick, Jennifer Lindsay
Published 2008

Modification, biological evaluation and 3D QSAR studies of novel 2-(1,3-diaryl- 4,5-dihydro-1H-pyrazol-5-yl)phenol derivatives as inhibitors of B-Raf kinase.

by Yu-Shun Yang, Fei Zhang, Dan-Jie Tang, Yong-Hua Yang, Hai-Liang Zhu
Published 2014-01-01

An engineered protein antagonist of K-Ras/B-Raf interaction

by Monique J. Kauke, Michael W. Traxlmayr, Jillian A. Parker, Jonathan D. Kiefer, Ryan Knihtila, John McGee, Greg Verdine, Carla Mattos, K. Dane Wittrup
Published 2017-07-01

Expression and Significance of Raf Kinase Inhibitory Protein 
in Lung Cancer

by Dayun YANG, Zhan QI
Published 2012-10-01

Longitudinal assessment of B-RAF V595E levels in the peripheral cell-free tumor DNA of a 10-year...

by Jung-Hyun Kim, Dana Hyunjung Ahn, Je-Sung Moon, Hyun-Jung Han, Kieun Bae, Kyong-Ah Yoon
Published 2021-01-01