Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism

by Yadav Sapkota, Valgerdur Steinthorsdottir, Andrew P. Morris, Amelie Fassbender, Nilufer Rahmioglu, Immaculata De Vivo, Julie E. Buring, Futao Zhang, Todd L. Edwards, Sarah Jones, Dorien O, Daniëlle Peterse, Kathryn M. Rexrode, Paul M. Ridker, Andrew J. Schork, Stuart MacGregor, Nicholas G. Martin, Christian M. Becker, Sosuke Adachi, Kosuke Yoshihara, Takayuki Enomoto, Atsushi Takahashi, Yoichiro Kamatani, Koichi Matsuda, Michiaki Kubo, Gudmar Thorleifsson, Reynir T. Geirsson, Unnur Thorsteinsdottir, Leanne M. Wallace, iPSYCH-SSI-Broad Group, Jian Yang, Digna R. Velez Edwards, Mette Nyegaard, Siew-Kee Low, Krina T. Zondervan, Stacey A. Missmer, Thomas D'Hooghe, Grant W. Montgomery, Daniel I. Chasman, Kari Stefansson, Joyce Y. Tung, Dale R. Nyholt
Published 2017-05-01

Chemistry, mineralogy, and grain properties at Namib and High dunes, Bagnold dune field, Gale crater, Mars: A synthesis of Curiosity rover observations

by Ehlmann, B. L., Edgett, K. S., Sutter, B., Achilles, C. N., Litvak, M. L., Lapotre, M. G. A., Sullivan, R., Fraeman, A. A., Arvidson, R. E., Blake, D. F., Bridges, N. T., Conrad, P. G., Cousin, A., Downs, R. T., Gabriel, T. S. J., Gellert, R., Hamilton, V. E., Hardgrove, C., Johnson, J. R., Kuhn, S., Mahaffy, P. R., Maurice, S., McHenry, M., Meslin, P.-Y., Ming, D. W., Minitti, M. E., Morookian, J. M., Morris, R. V., O'Connell-Cooper, C. D., Pinet, P. C., Rowland, S. K., Schröder, S., Siebach, K. L., Stein, N. T., Thompson, L. M., Vaniman, D. T., Vasavada, A. R., Wellington, D. F., Wiens, R. C., Yen, A. S.
Published 2017

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.

by Anubha Mahajan, Xueling Sim, Hui Jin Ng, Alisa Manning, Manuel A Rivas, Heather M Highland, Adam E Locke, Niels Grarup, Hae Kyung Im, Pablo Cingolani, Jason Flannick, Pierre Fontanillas, Christian Fuchsberger, Kyle J Gaulton, Tanya M Teslovich, N William Rayner, Neil R Robertson, Nicola L Beer, Jana K Rundle, Jette Bork-Jensen, Claes Ladenvall, Christine Blancher, David Buck, Gemma Buck, Noël P Burtt, Stacey Gabriel, Anette P Gjesing, Christopher J Groves, Mette Hollensted, Jeroen R Huyghe, Anne U Jackson, Goo Jun, Johanne Marie Justesen, Massimo Mangino, Jacquelyn Murphy, Matt Neville, Robert Onofrio, Kerrin S Small, Heather M Stringham, Ann-Christine Syvänen, Joseph Trakalo, Goncalo Abecasis, Graeme I Bell, John Blangero, Nancy J Cox, Ravindranath Duggirala, Craig L Hanis, Mark Seielstad, James G Wilson, Cramer Christensen, Ivan Brandslund, Rainer Rauramaa, Gabriela L Surdulescu, Alex S F Doney, Lars Lannfelt, Allan Linneberg, Bo Isomaa, Tiinamaija Tuomi, Marit E Jørgensen, Torben Jørgensen, Johanna Kuusisto, Matti Uusitupa, Veikko Salomaa, Timothy D Spector, Andrew D Morris, Colin N A Palmer, Francis S Collins, Karen L Mohlke, Richard N Bergman, Erik Ingelsson, Lars Lind, Jaakko Tuomilehto, Torben Hansen, Richard M Watanabe, Inga Prokopenko, Josee Dupuis, Fredrik Karpe, Leif Groop, Markku Laakso, Oluf Pedersen, Jose C Florez, Andrew P Morris, David Altshuler, James B Meigs, Michael Boehnke, Mark I McCarthy, Cecilia M Lindgren, Anna L Gloyn, T2D-GENES consortium and GoT2D consortium
Published 2015-01-01

ZikaPLAN: addressing the knowledge gaps and working towards a research preparedness network in the Americas

by Annelies Wilder-Smith, Raman Preet, Elizabeth B. Brickley, Ricardo Arraes de Alencar Ximenes, Demócrito de Barros Miranda-Filho, Celina Maria Turchi Martelli, Thália Velho Barreto de Araújo, Ulisses Ramos Montarroyos, Maria Elisabeth Moreira, Marília Dalva Turchi, Tom Solomon, Bart C. Jacobs, Carlos Pardo Villamizar, Lyda Osorio, Ana Maria Bispo de Filipps, Johan Neyts, Suzanne Kaptein, Ralph Huits, Kevin K. Ariën, Hugh J. Willison, Julia M. Edgar, Susan C. Barnett, Rosanna Peeling, Debi Boeras, Maria G. Guzman, Aravinda M. de Silva, Andrew K. Falconar, Claudia Romero-Vivas, Michael W. Gaunt, Alessandro Sette, Daniela Weiskopf, Louis Lambrechts, Helen Dolk, Joan K. Morris, Ieda M. Orioli, Kathleen M. O’Reilly, Laith Yakob, Joacim Rocklöv, Cristiane Soares, Maria Lúcia Brito Ferreira, Rafael Freitas de Oliveira Franca, Alexander R. Precioso, James Logan, Trudie Lang, Nina Jamieson, Eduardo Massad
Published 2019-01-01

Genome wide association identifies common variants at the SERPINA6/SERPINA1 locus influencing plasma cortisol and corticosteroid binding globulin.

by Jennifer L Bolton, Caroline Hayward, Nese Direk, John G Lewis, Geoffrey L Hammond, Lesley A Hill, Anna Anderson, Jennifer Huffman, James F Wilson, Harry Campbell, Igor Rudan, Alan Wright, Nicholas Hastie, Sarah H Wild, Fleur P Velders, Albert Hofman, Andre G Uitterlinden, Jari Lahti, Katri Räikkönen, Eero Kajantie, Elisabeth Widen, Aarno Palotie, Johan G Eriksson, Marika Kaakinen, Marjo-Riitta Järvelin, Nicholas J Timpson, George Davey Smith, Susan M Ring, David M Evans, Beate St Pourcain, Toshiko Tanaka, Yuri Milaneschi, Stefania Bandinelli, Luigi Ferrucci, Pim van der Harst, Judith G M Rosmalen, Stephen J L Bakker, Niek Verweij, Robin P F Dullaart, Anubha Mahajan, Cecilia M Lindgren, Andrew Morris, Lars Lind, Erik Ingelsson, Laura N Anderson, Craig E Pennell, Stephen J Lye, Stephen G Matthews, Joel Eriksson, Dan Mellstrom, Claes Ohlsson, Jackie F Price, Mark W J Strachan, Rebecca M Reynolds, Henning Tiemeier, Brian R Walker, CORtisol NETwork (CORNET) Consortium
Published 2014-07-01

Neonatal mortality in Kenyan hospitals: a multisite, retrospective, cohort study

by Grace Irimu, Morris Ogero, George Mbevi, David Gathara, Samuel Akech, Jalemba Aluvaala, Ambrose Agweyu, Mercy Chepkirui, Sylvia Omoke, Emma Namulala, Juma Vitalis, Rachel Inginia, Grace Ochieng, Lydia Thuranira, Esther Njiru, Charles Nzioki, Caren Emadau, Christine Manyasi, Fred Were, Magdalene Kuria, Mary Waiyego, Beth Maina, Edith Gicheha, Joseph Nganga, Esther Mwangi, Esther Muthiani, Mary Nguri, Samuel Soita, Margaret Waweru, Alfred Wanjau, Caroline Mwangi, John Wainaina, Livingstone Mumelo, Nyumbile Bonface, Wagura Mwangi, Penina Mwangi, Felistus Makokha, Josephine Ojigo, Bernadette Lusweti, Amilia Ngoda, Dolphine Mochache, Jane Mbungu, Joan Baswetty, Josephine Aritho, Beatrice Njambi, Zainab Kioni, Lucy Kinyua, Alice Oguda, Loise N. Mwangi, Nancy Mburu, Celestine Muteshi, Salome Okisa Muyale, Faith Mueni, Rosemary Mututa, Joyce Oketch, Orina Nyakina, Faith Njeru, Margaret Wanjiku Mwaura, Seline Kulubi, Susan Wanjala, Pauline Njeru, John Ollongo, Otieno George Obop, Jeska Kuya, Benjamin Tanui, Judith Onsongo, Peter Muigai, Arnest Namayi
Published 2021-05-01

EUROlinkCAT protocol for a European population-based data linkage study investigating the survival, morbidity and education of children with congenital anomalies

by Nathalie Lelong, Babak Khoshnood, David Tucker, Mika Gissler, Maria Loane, Ingeborg Barisic, Miriam Gatt, Kari Klungsoyr, Amanda Neville, Anna Pierini, Anke Rissmann, Oscar Zurriaga, Joan K Morris, Paula Braz, Vera Nelen, Judith Rankin, Ester Garne, Sue Jordan, Anna Heino, Silvia Baldacci, Michele Santoro, Alessio Coi, Lorena Mezzasalma, Daniel Thayer, Svetlana V Glinianaia, Hermien de Walle, Guy Thys, Anna Latos-Bielenska, Aurora Puccini, Elisa Ballardini, Wladimir Wertelecki, Carlos Matias Dias, Gianni Astolfi, James Densem, Joachim Tan, Joanne Emma Given, Hugh Claridge, Abigail Reid, Liz Limb, Gillian Briggs, Nicholas Connor, Stine Kjaer Urhoj, Mads Damkjær, Christina Neergaard Pedersen, Annarita Armaroli, Ljubica Boban, L Renée Lutke, Nicole H A Siemensma-Mühlenberg, Nathalie Bertille, Makan Rahshenas, Clara Cavero Carbonell, Laia Barrachina Bonet, Laura García Villodre, Anna Jamry-Dziurla, Sonja Kiuru-Kuhlefelt, Lyubov Yevtushok, Nataliia Zymak-Zakutnia, Diana Akhmedzhanova, Lyubov Ostapchuk, Oksana Tsizh, Serhii Lapchenko, Ausenda Machado, Ana João Santos, Liliana Antunes, Hanitra Randrianaivo-Ranjatoelina, Elly Den Hond, Olatz Mokoroa Carollo, Ieuan Scanlon
Published 2021-06-01

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.

by Sandosh Padmanabhan, Olle Melander, Toby Johnson, Anna Maria Di Blasio, Wai K Lee, Davide Gentilini, Claire E Hastie, Cristina Menni, Maria Cristina Monti, Christian Delles, Stewart Laing, Barbara Corso, Gerjan Navis, Arjan J Kwakernaak, Pim van der Harst, Murielle Bochud, Marc Maillard, Michel Burnier, Thomas Hedner, Sverre Kjeldsen, Björn Wahlstrand, Marketa Sjögren, Cristiano Fava, Martina Montagnana, Elisa Danese, Ole Torffvit, Bo Hedblad, Harold Snieder, John M C Connell, Morris Brown, Nilesh J Samani, Martin Farrall, Giancarlo Cesana, Giuseppe Mancia, Stefano Signorini, Guido Grassi, Susana Eyheramendy, H Erich Wichmann, Maris Laan, David P Strachan, Peter Sever, Denis Colm Shields, Alice Stanton, Peter Vollenweider, Alexander Teumer, Henry Völzke, Rainer Rettig, Christopher Newton-Cheh, Pankaj Arora, Feng Zhang, Nicole Soranzo, Timothy D Spector, Gavin Lucas, Sekar Kathiresan, David S Siscovick, Jian'an Luan, Ruth J F Loos, Nicholas J Wareham, Brenda W Penninx, Ilja M Nolte, Martin McBride, William H Miller, Stuart A Nicklin, Andrew H Baker, Delyth Graham, Robert A McDonald, Jill P Pell, Naveed Sattar, Paul Welsh, Global BPgen Consortium, Patricia Munroe, Mark J Caulfield, Alberto Zanchetti, Anna F Dominiczak
Published 2010-10-01

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.

by Bram P Prins, Ali Abbasi, Anson Wong, Ahmad Vaez, Ilja Nolte, Nora Franceschini, Philip E Stuart, Javier Guterriez Achury, Vanisha Mistry, Jonathan P Bradfield, Ana M Valdes, Jose Bras, Aleksey Shatunov, PAGE Consortium, International Stroke Genetics Consortium, Systemic Sclerosis consortium, Treat OA consortium, DIAGRAM Consortium, CARDIoGRAMplusC4D Consortium, ALS consortium, International Parkinson’s Disease Genomics Consortium, Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, CKDGen consortium, GERAD1 Consortium, International Consortium for Blood Pressure, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Inflammation Working Group of the CHARGE Consortium, Chen Lu, Buhm Han, Soumya Raychaudhuri, Steve Bevan, Maureen D Mayes, Lam C Tsoi, Evangelos Evangelou, Rajan P Nair, Struan F A Grant, Constantin Polychronakos, Timothy R D Radstake, David A van Heel, Melanie L Dunstan, Nicholas W Wood, Ammar Al-Chalabi, Abbas Dehghan, Hakon Hakonarson, Hugh S Markus, James T Elder, Jo Knight, Dan E Arking, Timothy D Spector, Bobby P C Koeleman, Cornelia M van Duijn, Javier Martin, Andrew P Morris, Rinse K Weersma, Cisca Wijmenga, Patricia B Munroe, John R B Perry, Jennie G Pouget, Yalda Jamshidi, Harold Snieder, Behrooz Z Alizadeh
Published 2016-06-01

Systems Approaches Evaluating the Perturbation of Xenobiotic Metabolism in Response to Cigarette Smoke Exposure in Nasal and Bronchial Tissues

by Anita R. Iskandar, Florian Martin, Marja Talikka, Walter K. Schlage, Radina Kostadinova, Carole Mathis, Julia Hoeng, Manuel C. Peitsch
Published 2013-01-01

Alterations in Serum Polyunsaturated Fatty Acids and Eicosanoids in Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)

by Bjoern Titz, Karsta Luettich, Patrice Leroy, Stephanie Boue, Gregory Vuillaume, Terhi Vihervaara, Kim Ekroos, Florian Martin, Manuel C. Peitsch, Julia Hoeng
Published 2016-09-01

Application of Fourier Transform Infra-red Evolved Gas Analysis (FT-IR-EGA) to the Study of Tobacco Curing

by Fenner RA, Lyons-Hart J, Lephardt JO, Teng DM
Published 1988-10-01

Assessment of Cigarette Smoking in Epidemiologic Studies

by Weitkunat R, Coggins CRE, Sponsiello-Wang Z, Kallischnigg G, Dempsey R
Published 2013-09-01

Cigarette Smoke Formation Studies: II. Smoke Distribution and Mainstream Pyrolytic Composition of Added 14C-Menthol (U)

by Jenkins R.W Jr., Newman R.H., Chavis M.K.
Published 1970-12-01

Organs-on-a-chip

by David Bovard, Anita Iskandar, Karsta Luettich, Julia Hoeng, Manuel C Peitsch
Published 2017-08-01

Cigarette Smoke Formation Studies: Vll. The Fate of (5-14C)-Methoprene in Cigarette Smoke

by Frisch A.F., Francis B.W., Chavis M.K., Jenkins R.W.
Published 1982-08-01

Comparing the preclinical risk profile of inhalable candidate and potential candidate modified risk tobacco products: A bridging use case

by Walter K. Schlage, Bjoern Titz, Anita Iskandar, Carine Poussin, Marco Van der Toorn, Ee Tsin Wong, Pascal Pratte, Serge Maeder, Jean-Pierre Schaller, Pavel Pospisil, Stephanie Boue, Grégory Vuillaume, Patrice Leroy, Florian Martin, Nikolai V. Ivanov, Manuel C. Peitsch, Julia Hoeng
Published 2020-01-01

Proteomics and Lipidomics in Inflammatory Bowel Disease Research: From Mechanistic Insights to Biomarker Identification

by Bjoern Titz, Raffaella M. Gadaleta, Giuseppe Lo Sasso, Ashraf Elamin, Kim Ekroos, Nikolai V. Ivanov, Manuel C. Peitsch, Julia Hoeng
Published 2018-09-01

A meta-analysis of microRNAs expressed in human aerodigestive epithelial cultures and their role as potential biomarkers of exposure response to nicotine-containing products

by Alain Sewer, Filippo Zanetti, Anita R. Iskandar, Emmanuel Guedj, Remi Dulize, Dariusz Peric, David Bornand, Carole Mathis, Florian Martin, Nikolai V. Ivanov, Manuel C. Peitsch, Julia Hoeng
Published 2020-01-01

Dietary, Metabolic, and Potentially Environmental Modulation of the Lysine Acetylation Machinery

by Go-Woon Kim, Goran Gocevski, Chao-Jung Wu, Xiang-Jiao Yang
Published 2010-01-01