Distinct expression requirements and rescue strategies for BEST1 loss- and gain-of-function mutations

by Qingqing Zhao, Yang Kong, Alec Kittredge, Yao Li, Yin Shen, Yu Zhang, Stephen H Tsang, Tingting Yang
Published 2021-06-01

You can keep your coat on

by Gregory J Bedwell, Alan N Engelman
Published 2021-06-01

Systematic screening of viral and human genetic variation identifies antiretroviral resistance and immune escape link

by Huyen Nguyen, Christian Wandell Thorball, Jacques Fellay, Jürg Böni, Sabine Yerly, Matthieu Perreau, Hans H Hirsch, Katharina Kusejko, Maria Christine Thurnheer, Manuel Battegay, Matthias Cavassini, Christian R Kahlert, Enos Bernasconi, Huldrych F Günthard, Roger D Kouyos, The Swiss HIV Cohort Study
Published 2021-06-01

Autism-associated SHANK3 missense point mutations impact conformational fluctuations and protein turnover at synapses

by Michael Bucher, Stephan Niebling, Yuhao Han, Dmitry Molodenskiy, Fatemeh Hassani Nia, Hans-Jürgen Kreienkamp, Dmitri Svergun, Eunjoon Kim, Alla S Kostyukova, Michael R Kreutz, Marina Mikhaylova
Published 2021-05-01

Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer’s disease

by Alexa Pichet Binette, Guillaume Theaud, François Rheault, Maggie Roy, D Louis Collins, Johannes Levin, Hiroshi Mori, Jae Hong Lee, Martin Rhys Farlow, Peter Schofield, Jasmeer P Chhatwal, Colin L Masters, Tammie Benzinger, John Morris, Randall Bateman, John CS Breitner, Judes Poirier, Julie Gonneaud, Maxime Descoteaux, Sylvia Villeneuve, DIAN Study Group, PREVENT-AD Research Group
Published 2021-05-01

Molecular machinery turns full circle

by Josep Rizo, Klaudia Jaczynska, Karolina P Stepien
Published 2021-06-01

Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions

by Mingzheng Wu, Samuel Minkowicz, Vasin Dumrongprechachan, Pauline Hamilton, Lei Xiao, Yevgenia Kozorovitskiy
Published 2021-04-01

Where ketamine and dopamine collide

by David J Marcus, Michael R Bruchas
Published 2021-06-01

Plexin-B2 controls the timing of differentiation and the motility of cerebellar granule neurons

by Eljo Van Battum, Celine Heitz-Marchaland, Yvrick Zagar, Stéphane Fouquet, Rohini Kuner, Alain Chédotal
Published 2021-06-01

The organizational principles of de-differentiated topographic maps in somatosensory cortex

by Peng Liu, Anastasia Chrysidou, Juliane Doehler, Martin N Hebart, Thomas Wolbers, Esther Kuehn
Published 2021-05-01

The push-to-open mechanism of the tethered mechanosensitive ion channel NompC

by Yang Wang, Yifeng Guo, Guanluan Li, Chunhong Liu, Lei Wang, Aihua Zhang, Zhiqiang Yan, Chen Song
Published 2021-06-01

Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction

by Muhammad Arif, Martina Klevstig, Rui Benfeitas, Stephen Doran, Hasan Turkez, Mathias Uhlén, Maryam Clausen, Johannes Wikström, Damla Etal, Cheng Zhang, Malin Levin, Adil Mardinoglu, Jan Boren
Published 2021-05-01

RSC primes the quiescent genome for hypertranscription upon cell-cycle re-entry

by Christine E Cucinotta, Rachel H Dell, Keean CA Braceros, Toshio Tsukiyama
Published 2021-05-01

Working together

by Regan Odongo, Tunahan Çakır
Published 2021-06-01

Permeabilization-free en bloc immunohistochemistry for correlative microscopy

by Kara A Fulton, Kevin L Briggman
Published 2021-05-01

Corticothalamic gating of population auditory thalamocortical transmission in mouse

by Baher A Ibrahim, Caitlin A Murphy, Georgiy Yudintsev, Yoshitaka Shinagawa, Matthew I Banks, Daniel A Llano
Published 2021-05-01

The critical importance of vouchers in genomics

by Janet C Buckner, Robert C Sanders, Brant C Faircloth, Prosanta Chakrabarty
Published 2021-06-01

Drp1 is required for AgRP neuronal activity and feeding

by Sungho Jin, Nal Ae Yoon, Zhong-Wu Liu, Jae Eun Song, Tamas L Horvath, Jung Dae Kim, Sabrina Diano
Published 2021-03-01

SORBS2 is a genetic factor contributing to cardiac malformation of 4q deletion syndrome patients

by Fei Liang, Bo Wang, Juan Geng, Guoling You, Jingjing Fa, Min Zhang, Hunying Sun, Huiwen Chen, Qihua Fu, Xiaoqing Zhang, Zhen Zhang
Published 2021-06-01

Erythrocyte CD55 mediates the internalization of Plasmodium falciparum parasites

by Bikash Shakya, Saurabh D Patel, Yoshihiko Tani, Elizabeth S Egan
Published 2021-05-01