Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial – the development of the DELTA2 guidance

by William Sones, Steven A. Julious, Joanne C. Rothwell, Craig Robert Ramsay, Lisa V. Hampson, Richard Emsley, Stephen J. Walters, Catherine Hewitt, Martin Bland, Dean A. Fergusson, Jesse A. Berlin, Doug Altman, Luke David Vale, Jonathan Alistair Cook
Published 2018-10-01

Dysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults

by Zhanghua Chen, Tingyu Yang, Douglas I. Walker, Duncan C. Thomas, Chenyu Qiu, Leda Chatzi, Tanya L. Alderete, Jeniffer S. Kim, David V. Conti, Carrie V. Breton, Donghai Liang, Elizabeth R. Hauser, Dean P. Jones, Frank D. Gilliland
Published 2020-12-01

A fatal case report of antibody-dependent enhancement of dengue virus type 1 following remote Zika virus infection

by Ashley N. Bonheur, Sarah Thomas, Sara H. Soshnick, Emily McGibbon, Alan P. Dupuis, Rene Hull, Sally Slavinski, Paula E. Del Rosso, Don Weiss, Danielle T. Hunt, Megan E. McCabe, Amy B. Dean, Rebecca Folkerth, Anne M. Laib, Susan J. Wong
Published 2021-08-01

Implementing genomic screening in diverse populations

by Noura S. Abul-Husn, Emily R. Soper, Giovanna T. Braganza, Jessica E. Rodriguez, Natasha Zeid, Sinead Cullina, Dean Bobo, Arden Moscati, Amanda Merkelson, Ruth J. F. Loos, Judy H. Cho, Gillian M. Belbin, Sabrina A. Suckiel, Eimear E. Kenny
Published 2021-02-01

WATER versus WATER II 2-Year Update: Comparing Aquablation Therapy for Benign Prostatic Hyperplasia in 30–80-cm3 and 80–150-cm3 Prostates

by David-Dan Nguyen, Neil Barber, Mo Bidair, Peter Gilling, Paul Anderson, Kevin C. Zorn, Gopal Badlani, Mitch Humphreys, Steven Kaplan, Ronald Kaufman, Alan So, Ryan Paterson, Larry Goldenberg, Dean Elterman, Mihir Desai, Jim Lingeman, Claus Roehrborn, Naeem Bhojani
Published 2021-03-01

Abstract: Osteogenic Effects of Dipyridamole Versus rhBMP-2 Using 3D-Printed Bioceramic Scaffolds in a Growing Alveolar Cleft Model

by Christopher D. Lopez, BA, Paulo G. Coelho, DDS, PhD, Lukasz Witek, MSci, PhD, Andrea Torroni, MD, Michael I Greenberg, BA, Dean L. Cuadrado, BA, Audrey M. Guarino, BA, Abrar J. Haque, BA, Bruce N. Cronstein, MD, Roberto L. Flores, MD
Published 2018-09-01

A phase II trial of durvalumab and tremelimumab in metastatic, non‐urothelial carcinoma of the urinary tract

by Michal Sarfaty, Karissa Whiting, Min Yuen Teo, Chung‐Han Lee, Vanessa Peters, Jennifer Durocher, Ashley M. Regazzi, Asia S. McCoy, Grace Hettich, Achim A. Jungbluth, Hikmat Al‐Ahmadie, Irina Ostrovnaya, Joshua Chaim, Dean F. Bajorin, Jonathan E. Rosenberg, Gopa Iyer, Samuel A. Funt
Published 2021-02-01

The development and validation of a prognostic model to PREDICT Relapse of depression in adult patients in primary care: protocol for the PREDICTR study

by Andrew S. Moriarty, Lewis W. Paton, Kym I. E. Snell, Richard D. Riley, Joshua E. J. Buckman, Simon Gilbody, Carolyn A. Chew-Graham, Shehzad Ali, Stephen Pilling, Nick Meader, Bob Phillips, Peter A. Coventry, Jaime Delgadillo, David A. Richards, Chris Salisbury, Dean McMillan
Published 2021-07-01

MYC and Twist1 cooperate to drive metastasis by eliciting crosstalk between cancer and innate immunity

by Renumathy Dhanasekaran, Virginie Baylot, Minsoon Kim, Sibu Kuruvilla, David I Bellovin, Nia Adeniji, Anand Rajan KD, Ian Lai, Meital Gabay, Ling Tong, Maya Krishnan, Jangho Park, Theodore Hu, Mustafa A Barbhuiya, Andrew J Gentles, Kasthuri Kannan, Phuoc T Tran, Dean W Felsher
Published 2020-01-01

Collaborative case management to aid return to work after long-term sickness absence: a pilot randomised controlled trial

by Cassandra Kenning, Karina Lovell, Mark Hann, Raymond Agius, Penny E Bee, Carolyn Chew-Graham, Peter A Coventry, Christina M van der Feltz-Cornelis, Simon Gilbody, Gillian Hardy, Stephen Kellett, David Kessler, Dean McMillan, David Reeves, Joanne Rick, Matthew Sutton, Peter Bower
Published 2018-01-01

Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Protocol: A Randomized Clinical Trial

by Sophia Kwon, Jessica Riggs, George Crowley, Rachel Lam, Isabel R. Young, Christine Nayar, Maria Sunseri, Mena Mikhail, Dean Ostrofsky, Arul Veerappan, Rachel Zeig-Owens, Theresa Schwartz, Hilary Colbeth, Mengling Liu, Mary Lou Pompeii, David St-Jules, David J. Prezant, Mary Ann Sevick, Anna Nolan
Published 2020-09-01

Exome sequencing reveals a high prevalence of BRCA1 and BRCA2 founder variants in a diverse population-based biobank

by Noura S. Abul-Husn, Emily R. Soper, Jacqueline A. Odgis, Sinead Cullina, Dean Bobo, Arden Moscati, Jessica E. Rodriguez, CBIPM Genomics Team, Regeneron Genetics Center, Ruth J. F. Loos, Judy H. Cho, Gillian M. Belbin, Sabrina A. Suckiel, Eimear E. Kenny
Published 2019-12-01

This Article Corrects: “Systemwide Clinical Ultrasound Program Development: An Expert Consensus Model”

by Robert Strony, Jennifer R. Marin, John Bailitz, Anthony J. Dean, Mike Blaivas, Vivek Tayal, Chris Raio, Rachel Liu, Aimee Woods, Michael Zwank, Matthew Fields, Alyssa Abo, Stan Wu, Tarina Kang, Teresa Liu, Megan Leo, Courtney Smalley, Jerry Chiricolo, Mikaela Chilstrom, Resa E. Lewiss
Published 2018-08-01

Systemwide Clinical Ultrasound Program Development: An Expert Consensus Model

by Robert Strony, Jennifer R. Marin, John Bailitz, Anthony J. Dean, Mike Blaivas, Vivek Tayal, Chris Raio, Rachel Liu, Aimee Woods, Michael Zwank, Matthew Fields, Alyssa Abo, Stan Wu, Tarina Kang, Teresa Liu, Megan Leo, Courtney Smalley, Jerry Chiricolo, Mikaela Chilstrom, Resa E. Lewiss
Published 2018-06-01

399 Cosibelimab, an anti-PD-L1 antibody: preliminary safety and efficacy results from a global, multicohort phase 1 clinical trial

by Dean Harris, Daniel Brungs, Rahul Ladwah, Andrew Mant, Margaret McGrath, Andrea Tazbirkova, Andrey Akopov, Natalia Fadeeva, Boris Kasparov, Nadezhda Kovalenko, Vadim Kozlov, Fedor Moiseenko, Vasiliy Oschepkov, Piotr Koralewski, Dariusz Kowalski, Iwona Lugowska, Chaiyut Charoentumn, Arunee Dechaphunkul, Virote Sriuranpong, James Oliviero, Philip Clingan
Published 2020-11-01

Community Pharmacies Mood Intervention Study (CHEMIST): feasibility and external pilot randomised controlled trial protocol

by Elizabeth Littlewood, Shehzad Ali, Jay Badenhorst, Della Bailey, Clare Bambra, Carolyn Chew-Graham, Elizabeth Coleman, Suzanne Crosland, Samantha Gascoyne, Simon Gilbody, Catherine Hewitt, Claire Jones, Ada Keding, Charlotte Kitchen, Dean McMillan, Caroline Pearson, Shelley Rhodes, Claire Sloan, Adam Todd, Michelle Watson, Cate Whittlesea, David Ekers
Published 2019-05-01

Treatment of Metastatic Extramammary Paget Disease with Combination Ipilimumab and Nivolumab: A Case Report

by Brendan John Guercio, Gopa Iyer, Wajih Zaheer Kidwai, Mario E. Lacouture, Soleen Ghafoor, Anthony M. Rossi, David N. Assis, Ying-Bei Chen, Klaus J. Busam, Yelena Y. Janjigian, Komal Jhaveri, Darren R. Feldman, Anne Capozzi, Vanessa Figueroa, Dean F. Bajorin, Jonathan E. Rosenberg, Travis J. Hollmann, Samuel A. Funt
Published 2021-03-01

Clinical effectiveness, cost-effectiveness and acceptability of low-intensity interventions in the management of obsessive–compulsive disorder: the Obsessive–Compulsive Treatment E...

by Karina Lovell, Peter Bower, Judith Gellatly, Sarah Byford, Penny Bee, Dean McMillan, Catherine Arundel, Simon Gilbody, Lina Gega, Gillian Hardy, Shirley Reynolds, Michael Barkham, Patricia Mottram, Nicola Lidbetter, Rebecca Pedley, Jo Molle, Emily Peckham, Jasmin Knopp-Hoffer, Owen Price, Janice Connell, Margaret Heslin, Christopher Foley, Faye Plummer, Christopher Roberts
Published 2017-06-01

Prioritization of Realignment Associated With Superior Clinical Outcomes for Cervical Deformity Patients

by Katherine E. Pierce, Peter G. Passias, Avery E. Brown, Cole A. Bortz, Haddy Alas, Lara Passfall, Oscar Krol, Nicholas Kummer, Renaud Lafage, Dean Chou, Douglas C. Burton, Breton Line, Eric Klineberg, Robert Hart, Jeffrey Gum, Alan Daniels, Kojo Hamilton, Shay Bess, Themistocles Protopsaltis, Christopher Shaffrey, Frank A. Schwab, Justin S. Smith, Virginie Lafage, Christopher Ames
Published 2021-09-01

Practical help for specifying the target difference in sample size calculations for RCTs: the DELTA2 five-stage study, including a workshop

by Jonathan A Cook, Steven A Julious, William Sones, Lisa V Hampson, Catherine Hewitt, Jesse A Berlin, Deborah Ashby, Richard Emsley, Dean A Fergusson, Stephen J Walters, Edward CF Wilson, Graeme MacLennan, Nigel Stallard, Joanne C Rothwell, Martin Bland, Louise Brown, Craig R Ramsay, Andrew Cook, David Armstrong, Douglas Altman, Luke D Vale
Published 2019-10-01