Transcriptional Reprogramming and Resistance to Colonic Mucosal Injury in Poly(ADP-ribose) Polymerase 1 (PARP1)-deficient Mice

by Larmonier, Claire B., Shehab, Kareem W., Laubitz, Daniel, Jamwal, Deepa R., Ghishan, Fayez K., Kiela, Pawel R.
Published 2016

Disialylated apolipoprotein C-III proteoform is associated with improved lipids in prediabetes and type 2 diabetes

by Koska, Juraj, Yassine, Hussein, Trenchevska, Olgica, Sinari, Shripad, Schwenke, Dawn C., Yen, Frances T., Billheimer, Dean, Nelson, Randall W., Nedelkov, Dobrin, Reaven, Peter D.
Published 2016

Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2–related factors 1 and 2 (NRF1 and NRF2)

by Tian, Wang, de la Vega, Montserrat Rojo, Schmidlin, Cody J., Ooi, Aikseng, Zhang, Donna D.
Published 2018

Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase

by Wales, Jessica A., Chen, Cheng-Yu, Breci, Linda, Weichsel, Andrzej, Bernier, Sylvie G., Sheppeck, James E., Solinga, Robert, Nakai, Takashi, Renhowe, Paul A., Jung, Joon, Montfort, William R.
Published 2018

Structural analyses of key features in the KANK1·KIF21A complex yield mechanistic insights into the cross-talk between microtubules and the cell cortex

by Weng, Zhuangfeng, Shang, Yuan, Yao, Deqiang, Zhu, Jinwei, Zhang, Rongguang
Published 2018

Protonation equilibria and pore-opening structure of the dual-histidine influenza B virus M2 transmembrane proton channel from solid-state NMR

by Williams, Jonathan K., Shcherbakov, Alexander A., Wang, Jun, Hong, Mei
Published 2017

P2X7 receptor antagonism prevents IL-1β release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy

by Khalafalla, Mahmoud G., Woods, Lucas T., Camden, Jean M., Khan, Aslam A., Limesand, Kirsten H., Petris, Michael J., Erb, Laurie, Weisman, Gary A.
Published 2017

Matriptase-2 suppresses hepcidin expression by cleaving multiple components of the hepcidin induction pathway

by Wahedi, Mastura, Wortham, Aaron M., Kleven, Mark D., Zhao, Ningning, Jue, Shall, Enns, Caroline A., Zhang, An-Sheng
Published 2017

Nuclear insulin-like growth factor 1 receptor phosphorylates proliferating cell nuclear antigen and rescues stalled replication forks after DNA damage

by Waraky, Ahmed, Lin, Yingbo, Warsito, Dudi, Haglund, Felix, Aleem, Eiman, Larsson, Olle
Published 2017

Rapid Renal Regulation of Peroxisome Proliferator-activated Receptor γ Coactivator-1α by Extracellular Signal-Regulated Kinase 1/2 in Physiological and Pathological Conditions

by Collier, Justin B., Whitaker, Ryan M., Eblen, Scott T., Schnellmann, Rick G.
Published 2016

The KIM-family protein-tyrosine phosphatases use distinct reversible oxidation intermediates: Intramolecular or intermolecular disulfide bond formation

by Machado, Luciana E. S. F., Shen, Tun-Li, Page, Rebecca, Peti, Wolfgang
Published 2017

Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury

by Dupre, Tess V., Doll, Mark A., Shah, Parag P., Sharp, Cierra N., Siow, Deanna, Megyesi, Judit, Shayman, James, Bielawska, Alicja, Bielawski, Jacek, Beverly, Levi J., Hernandez-Corbacho, Maria, Clarke, Christopher J., Snider, Ashley J., Schnellmann, Rick G., Obeid, Lina M., Hannun, Yusuf A., Siskind, Leah J.
Published 2017