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Medicine
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somatic hypermutation
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2by Filip Senigl, Yaakov Maman, Ravi K. Dinesh, Jukka Alinikula, Rashu B. Seth, Lubomira Pecnova, Arina D. Omer, Suhas S.P. Rao, David Weisz, Jean-Marie Buerstedde, Erez Lieberman Aiden, Rafael Casellas, Jiri Hejnar, David G. Schatz“...Summary: Somatic hypermutation (SHM) introduces point mutations into immunoglobulin (Ig) genes...”
Published 2019-12-01
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6by Jean-Marie Buerstedde, Jukka Alinikula, Hiroshi Arakawa, Jessica J McDonald, David G Schatz“...Somatic hypermutation (SH) generates point mutations within rearranged immunoglobulin (Ig) genes...”
Published 2014-04-01
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7“...Somatic hypermutation (SHM) of immunoglobulin (Ig) genes plays a key role in antibody mediated...”
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10by Gallagher, Aoife M.“... in affinity maturation of the response. This diversification is currently ascribed to somatic hypermutation...”
Published 2002
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11by Lewis, Teresa D.“... molecular events (i.e. somatic hypermutation) that occur during the specific immune response. The absence...”
Published 2000
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13by Edward J. SteeleSubjects: “...somatic hypermutation...”
Published 2017-11-01
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14by Sharma, Shikha“... surface display combined with mutagenesis driven by somatic hypermutation (SHM) was investigated...”
Published 2011
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15by Steele, Kathryn Helen“... was to test whether the somatic hypermutation (SHM) gene diversification activity of B cells could be combined...”
Published 2013
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16“...The processes of somatic hypermutation (SHM) and class switch recombination introduced...”
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17“... that transgenes integrated into HEK293FT could efficiently accumulate somatic hypermutations (SHM) after repeated...”
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18by Jeannine A Ott, Caitlin D Castro, Thaddeus C Deiss, Yuko Ohta, Martin F Flajnik, Michael F CriscitielloSubjects: “...somatic hypermutation...”
Published 2018-04-01
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19“...To generate high affinity antibodies during an immune response, B cells undergo somatic...”
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20“... genes by the three distinct yet related processes of somatic hypermutation (SHM), class switch...”
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Article