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121“...DNA polymerase µ is involved in DNA repair, V(D)J recombination and likely somatic hypermutation...”
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122by Glen M Borchert, Nathaniel W Holton, Kevin A Edwards, Laura A Vogel, Erik D Larson“...Somatic hypermutation introduces base substitutions into the rearranged and expressed...”
Published 2010-07-01
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123“.... Subsequently, antigen stimulation results somatic hypermutation in those genes encoding variable region...”
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124by Carolyn E. Rydyznski, Stacey A. Cranert, Julian Q. Zhou, Heping Xu, Steven H. Kleinstein, Harinder Singh, Stephen N. Waggoner“...Summary: Somatic hypermutation of immunoglobulin sequences in germinal center (GC) reactions must...”
Published 2018-09-01
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125“.... We show that enforced nuclear localization of AID in G1 phase accelerates somatic hypermutation...”
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126“...V(D)J recombination and somatic hypermutation (SHM) are the primary mechanisms for diversification...”
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127by Briney, Bryan Scott“... and extensive somatic hypermutation. Two exceptionally broad, potently neutralizing HIV-specific antibodies, PG9...”
Published 2012
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128by Hoehn, Kenneth“... by somatic hypermutation. Chapter 4 expands this model to incorporate previously defined empirical models...”
Published 2017
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129by Lucier, Mark R“... gene conversion and untemplated somatic hypermutation could be taking place in fetal spleen. Evidence...”
Published 1999
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131by Christopher M Collins, Christopher D Scharer, Thomas J Murphy, Jeremy M Boss, Samuel H Speck“... switched plasma cells display no somatic hypermutation regardless of infection status. Taken together...”
Published 2020-04-01
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132“... description of an <it>in vitro </it>somatic hypermutation assay in this cell line, it should now be possible...”
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133by Alberto Cagigi, Likun Du, Linh Vu Phuong Dang, Sven Grutzmeier, Ann Atlas, Francesca Chiodi, Qiang Pan-Hammarström, Anna Nilsson“...Class switch recombination and somatic hypermutation occur in mature B-cells in response to antigen...”
Published 2009-01-01
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134by Philip Savage“... in apoptotic sensitivity. In VDJ recombination and somatic hypermutation over 95% of the cells involved undergo...”
Published 2020-06-01
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135by Emanuela Carlotti, David Wrench, Guglielmo Rosignoli, Jacek Marzec, Ajanthah Sangaralingam, Lena Hazanov, Miri Michaeli, Simon Hallam, Tracy Chaplin, Sameena Iqbal, Maria Calaminici, Bryan Young, Ramit Mehr, Peter Campbell, Jude Fitzgibbon, John G Gribben“... and how it evolves is still unclear. The analysis of the pattern of somatic hypermutation...”
Published 2015-01-01
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136by Diana Mechtcheriakova, Yury Sobanov, Gabriele Holtappels, Erika Bajna, Martin Svoboda, Markus Jaritz, Claus Bachert, Erika Jensen-Jarolim“... and is critically involved in class switch recombination and somatic hypermutation of immunoglobulin loci...”
Published 2011-01-01
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137by Harries, Helen Elizabeth“... development. Somatic hypermutation patterns in VH5-Ca sequences were indicative of superantigen selection...”
Published 2007
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138by Laila Shehata, Daniel P. Maurer, Anna Z. Wec, Asparouh Lilov, Elizabeth Champney, Tingwan Sun, Kimberly Archambault, Irina Burnina, Heather Lynaugh, Xiaoyong Zhi, Yingda Xu, Laura M. Walker“... compared with naive B cell-derived mAbs. Somatic hypermutation (SHM) is inversely associated with all three...”
Published 2019-09-01
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139by Cinque Soto, Gilad Ofek, M Gordon Joyce, Baoshan Zhang, Krisha McKee, Nancy S Longo, Yongping Yang, Jinghe Huang, Robert Parks, Joshua Eudailey, Krissey E Lloyd, S Munir Alam, Barton F Haynes, NISC Comparative Sequencing Program, James C Mullikin, Mark Connors, John R Mascola, Lawrence Shapiro, Peter D Kwong“... pathway from a single time point. Mutational analysis indicated somatic hypermutation of the 2nd-heavy...”
Published 2016-01-01
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140by Monique R. Bennett, Jinhui Dong, Robin G. Bombardi, Cinque Soto, Helen M. Parrington, Rachel S. Nargi, Clara T. Schoeder, Marcus B. Nagel, Kevin L. Schey, Jens Meiler, Eric P. Skaar, James E. Crowe“... that somatic hypermutation in the development of these antibodies hinders rather than fine-tunes the immune...”
Published 2019-10-01
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Article